Results 191 to 200 of about 6,245 (267)

White Light Enhances Adhesive Strength Between Epidermal and Inner Tissues of Pea Epicotyls via Accumulation of Cell Wall-Bound p-Coumaric Acid. [PDF]

Physiol Plant
Shimizu Y, Wakabayashi K, Miyamoto K, Soga K.   +3 more
europepmc   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

The FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi, Ayumu Takahashi, So Murakami, Nami Adachi, Tina Fujimoto, Yohta Fukuda, Taku Yamashita, Tsuyoshi Inoue, Hirofumi Tsujino   +8 more
wiley   +1 more source

Short-Chain Fatty Acids Elicit Differential Expression of Growth Factors and Pro-Inflammatory Cytokines in Immortalized Rat Enteric Glial Cells. [PDF]

Nutrients
Beltran MM, Defries DM.
europepmc   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

HPPA as assay substrate for improved capturing of sample variability during cut point analyses in immunogenicity testing. [PDF]

Bioanalysis
Jordan G, Pöhler A, Jany C, Bach T, Staack RF.   +4 more
europepmc   +1 more source

Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome

The FEBS Journal, EarlyView.
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer, Guiseppa de Rocco, Moritz Völker‐Albert, Ignasi Forne, Nicoletta Landsberger, Axel Imhof, Shibojyoti Lahiri   +6 more
wiley   +1 more source

Effect of Moderate Heat on TCE Reductive Dechlorination Rates in Groundwater

Groundwater Monitoring &Remediation, EarlyView.
Abstract Low‐temperature heating (in the mesophilic range of ~15 to 40 °C) of contaminated aquifers offers the prospect of increasing the rates for biotic and abiotic treatment of volatile organic compounds. Thermal In Situ Sustainable Remediation (TISR®) is one of the approaches available to implement low temperature heating.
David L. Freedman, Nicholas Cotter, Craig Divine, Shandra Justicia‐Leone   +3 more
wiley   +1 more source

Propionate attenuates osteoarthritis progression by regulating the gut-joint axis. [PDF]

Front Immunol
Han S, Cho KH, Na HS, Jhun J, Moon YM, Choi JW, Kim SJ, Cho ML.   +7 more
europepmc   +1 more source

ヘム　タンパクシツ　ニ　オケル　ヘムプロピオンサン　ソクサ　ノ　キノウテキ　ヤクワリ　カイメイ [PDF]

Harada, Katsuyoshi, ハラダ, カツヨシ, 原田, 勝好   +2 more
core  

Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis

Immunology, EarlyView.
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay, Mariem Garci, Ahmed Baligh Laaribi, Nabil Mathlouthi, Imene Ouzari   +4 more
wiley   +1 more source