Results 251 to 260 of about 129,614 (305)
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Propofol and the electroencephalogram
Clinical Neurophysiology, 2010Propofol is an emulsion formulation of 2,6 diisopropylphenol developed in 1975. Widely recognized, it offers beneficial effects compared with other sedative drugs. Propofol is used in several clinical situations including multiple surgical procedures and critical-care medical conditions.
Daniel San-Juan, Andrew J Cole
exaly +3 more sources
Effects of propofol on cancer development and chemotherapy: Potential mechanisms
European Journal of Pharmacology, 2018Propofol (2, 6‐diisopropylphenol) is the commonly used intravenous sedative‐hypnotic agent. Accumulating evidence shows that propofol affects cancer development by direct and indirect ways.
Lining Huang, Rongtian Kang
exaly +2 more sources
Journal of clinical anesthesia, 2023
STUDY OBJECTIVE In many countries, the combination of propofol and opioid is used as the preferred sedative regime during ERCP. However, the most serious risks of propofol sedation are oxygen deficiency and hypotension. Compared to midazolam, remimazolam
Shuan Dong +11 more
semanticscholar +1 more source
STUDY OBJECTIVE In many countries, the combination of propofol and opioid is used as the preferred sedative regime during ERCP. However, the most serious risks of propofol sedation are oxygen deficiency and hypotension. Compared to midazolam, remimazolam
Shuan Dong +11 more
semanticscholar +1 more source
2008
The hypnotic agent propofol has pharmacokinetic characteristics that allow for rapid onset and offset of drug effect and fast elimination from the body. Elderly patients show a greater sensitivity to the hypnotic effect of propofol. The drug is extensively metabolized in the liver through the cytochrome P450 system and glucuronidation, with potential ...
Vanlersberghe, C., Camu, Fréderic
openaire +3 more sources
The hypnotic agent propofol has pharmacokinetic characteristics that allow for rapid onset and offset of drug effect and fast elimination from the body. Elderly patients show a greater sensitivity to the hypnotic effect of propofol. The drug is extensively metabolized in the liver through the cytochrome P450 system and glucuronidation, with potential ...
Vanlersberghe, C., Camu, Fréderic
openaire +3 more sources
Journal of Clinical Anesthesia, 1989
A review of the pharmacology of propofol, a new IV anesthetic agent, is presented. Solubilized in a soybean emulsion, propofol is one of a series of sterically hindered phenols that exhibit anesthetic activity. Induction of anesthesia with propofol may be associated with pain on injection, apnea, and a reduction in arterial blood pressure (BP) and ...
M A, Skues, C, Prys-Roberts
openaire +2 more sources
A review of the pharmacology of propofol, a new IV anesthetic agent, is presented. Solubilized in a soybean emulsion, propofol is one of a series of sterically hindered phenols that exhibit anesthetic activity. Induction of anesthesia with propofol may be associated with pain on injection, apnea, and a reduction in arterial blood pressure (BP) and ...
M A, Skues, C, Prys-Roberts
openaire +2 more sources
Anaesthesia, 2020
Propofol‐based total intravenous anaesthesia is well known for its smooth, clear‐headed recovery and anti‐emetic properties, but there are also many lesser known beneficial properties that can potentially influence surgical outcome.
M. Irwin, C. Chung, K. Y. Ip, M. Wiles
semanticscholar +1 more source
Propofol‐based total intravenous anaesthesia is well known for its smooth, clear‐headed recovery and anti‐emetic properties, but there are also many lesser known beneficial properties that can potentially influence surgical outcome.
M. Irwin, C. Chung, K. Y. Ip, M. Wiles
semanticscholar +1 more source
Anesthesiology, 2005
Propofol is a potent lipophilic anesthetic that was initially formulated in Cremophor El for human use. Because of the occurrence of Cremophor EL anaphylaxis and improvements in the quality of lipid emulsions, it was ultimately brought to market as 1% propofol formulated in 10% soybean oil emulsion.
Max T. Baker +2 more
openaire +2 more sources
Propofol is a potent lipophilic anesthetic that was initially formulated in Cremophor El for human use. Because of the occurrence of Cremophor EL anaphylaxis and improvements in the quality of lipid emulsions, it was ultimately brought to market as 1% propofol formulated in 10% soybean oil emulsion.
Max T. Baker +2 more
openaire +2 more sources
European Journal of Anaesthesiology, 2019
BACKGROUND Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most complex gastrointestinal endoscopic procedures. Currently, it is still unclear which sedation regimen best facilitates an ERCP.
S. Eberl +6 more
semanticscholar +1 more source
BACKGROUND Endoscopic retrograde cholangiopancreatography (ERCP) is one of the most complex gastrointestinal endoscopic procedures. Currently, it is still unclear which sedation regimen best facilitates an ERCP.
S. Eberl +6 more
semanticscholar +1 more source
Effects of propofol on ischemia-reperfusion and traumatic brain injury.
Journal of critical care, 2019Oxidative stress exacerbates brain damage following ischemia-reperfusion and traumatic brain injury (TBI). Management of TBI and critically ill patients commonly involves use of propofol, a sedation medication that acts as a general anesthetic with ...
Melissa A. Hausburg +8 more
semanticscholar +1 more source