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Density Regression Based on Proportional Hazards Family [PDF]

open access: yesEntropy, 2015
This paper develops a class of density regression models based on proportional hazards family, namely, Gamma transformation proportional hazard (Gt-PH) model . Exact inference for the regression parameters and hazard ratio is derived.
Wei Dang, Keming Yu
doaj   +4 more sources

The Impact of Violation of the Proportional Hazards Assumption on the Calibration of the Cox Proportional Hazards Model [PDF]

open access: yesEpidemiology, Biostatistics and Public Health
INTRODUCTION The Cox proportional hazards regression model is frequently used to develop clinical prediction models for time-to-event outcomes, allowing clinicians to estimate an individual’s risk of experiencing the outcome within specified time ...
Peter Austin, Daniele Giardiello
doaj   +2 more sources

On Cox proportional hazards model performance under different sampling schemes. [PDF]

open access: yesPLoS ONE, 2023
Cox's proportional hazards model (PH) is an acceptable model for survival data analysis. This work investigates PH models' performance under different efficient sampling schemes for analyzing time to event data (survival data). We will compare a modified
Hani Samawi, Lili Yu, JingJing Yin
doaj   +3 more sources

Efficient Post-Shrinkage Estimation Strategies in High-Dimensional Cox’s Proportional Hazards Models [PDF]

open access: yesEntropy
Regularization methods such as LASSO, adaptive LASSO, Elastic-Net, and SCAD are widely employed for variable selection in statistical modeling. However, these methods primarily focus on variables with strong effects while often overlooking weaker signals,
Syed Ejaz Ahmed   +2 more
doaj   +2 more sources

Verticox+: vertically distributed Cox proportional hazards model with improved privacy guarantees [PDF]

open access: yesComplex & Intelligent Systems
Federated learning allows us to run machine learning algorithms on decentralized data when data sharing is not permitted due to privacy concerns. Various models have been adapted to use in a federated setting.
Florian van Daalen   +4 more
doaj   +2 more sources

Limitations of using COX proportional hazards model in cardiovascular research [PDF]

open access: yesCardiovascular Diabetology
The article by Zhao et al. titled “Associations of Triglyceride-Glucose (TyG) Index with Chest Pain Incidence and Mortality among the U.S. Population” provides valuable insights into the positive correlation between the TyG index and chest pain incidence,
Nan Jiang, Yongfa Wu, Chengjia Li
doaj   +2 more sources

Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent [PDF]

open access: yesJournal of Statistical Software, 2011
We introduce a pathwise algorithm for the Cox proportional hazards model, regularized by convex combinations of l1 and l2 penalties (elastic net). Our algorithm fits via cyclical coordinate descent, and employs warm starts to find a solution along a ...
Noah Simon   +3 more
doaj   +1 more source

Cox proportional hazards regression in small studies of predictive biomarkers [PDF]

open access: yesScientific Reports
Predictive biomarkers are essential for personalized medicine since they select the best treatment for a specific patient. However, of all biomarkers that are evaluated, only few are eventually used in clinical practice.
K. Jóźwiak   +4 more
doaj   +2 more sources

Cox proportional hazards model with Bayesian neural network for survival prediction [PDF]

open access: yesScientific Reports
Survival analysis plays a crucial aspect in medical research and other domains where understanding the time-to-events is paramount. In this study, we present a novel approach for estimating survival outcomes that combines Bayesian neural networks with ...
Fojan Faghiri, Akram Kohansal
doaj   +2 more sources

BHCox: Bayesian heredity-constrained Cox proportional hazards models for detecting gene-environment interactions [PDF]

open access: yesBMC Bioinformatics
Background Gene-environment (G × E) interactions play a critical role in understanding the etiology of diseases and exploring the factors that affect disease prognosis.
Na Sun   +6 more
doaj   +2 more sources

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