Results 151 to 160 of about 459,261 (336)

Cox Proportional Hazards Regression for Interval Censored data with an Application to College Entrance and Parental Job Loss [PDF]

, 2022
Han Jo Kim, SungHun Kim, Eunjee Lee
openalex   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

ADVANCES IN RENEWAL DECISION-MAKING UTILISING THE PROPORTIONAL HAZARDS MODEL WITH VIBRATION COVARIATES

South African Journal of Industrial Engineering, 2012
<p>ENGLISH ABSTRACT: Increased competitiveness in the production world necessitates improved maintenance strategies to increase availabilities and drive down cost .
Pieter-Jan Vlok, Jasper L. Coetzee
doaj  

A New Data Augmentation Method for Bayesian Semiparametric Proportional Hazards Model Analyzing Arbitrarily Censored Data [PDF]

, 2023
Xin Zhi, Xiaoyan Lin, Lianming Wang
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Pseudo-Observation Approach for Length-Biased Cox Proportional Hazards Model. [PDF]

Biom J
Akbari M, Rad NN, Chen DG.
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Cox Proportional Hazards Model for Event-Free Survival (Total Mortality and Heart Transplantation)^*.

Maria Tereza Sampaio de Sousa Lira (21169240), Silas Ramos Furquim (21169243), Daniel Catto de Marchi (21169246), Pamela Camara Maciel (21169249), Rafael Cavalcanti Tourinho Dantas (21169252), Bruno Biselli (4957378), Paulo Roberto Chizzola (4846249), Robinson Tadeu Munhoz (21169255), Felix José Alvarez Ramires (10372223), Barbara Maria Ianni (9091697), Fábio Fernandes (383385), Silvia Moreira Ayub-Ferreira (4846234), Eduardo Gomes Lima (4895998), Edimar Alcides Bocchi (7856090)   +13 more
openalex   +1 more source