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Adjusting for bias introduced by instrumental variable estimation in the Cox Proportional Hazards Model [PDF]

open access: yesBiostatistics, 2017
Instrumental variable (IV) methods are widely used for estimating average treatment effects in the presence of unmeasured confounders. However, the capability of existing IV procedures, and most notably the two-stage residual inclusion (2SRI) procedure ...
Goodney, Philip P.   +4 more
core   +2 more sources

A Bayesian approach for analyzing partly interval-censored data under the proportional hazards model. [PDF]

open access: yesStat Methods Med Res, 2020
Partly interval-censored time-to-event data often occur in biomedical studies of diseases where periodic medical examinations for symptoms of interest are necessary.
Pan C, Cai B, Wang L.
europepmc   +2 more sources

Survival analysis-part 2: Cox proportional hazards model. [PDF]

open access: yesIndian J Thorac Cardiovasc Surg, 2021
Deo SV, Deo V, Sundaram V.
europepmc   +2 more sources

Using fractional polynomials and restricted cubic splines to model non‐proportional hazards or time‐varying covariate effects in the Cox regression model

open access: yesStatistics in Medicine, 2021
The Cox proportional hazards model is used extensively in clinical and epidemiological research. A key assumption of this model is that of proportional hazards.
P. Austin, Jiming Fang, Douglas S. Lee
semanticscholar   +1 more source

Identification of a competing risks model with unknown transformations of latent failure times [PDF]

open access: yes, 2005
This paper is concerned with identification of a competing risks model with unknown transformations of latent failure times. The model in this paper includes, as special cases, competing risks versions of proportional hazards, mixed proportional ...
Lee, S.
core   +8 more sources

Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent.

open access: yesJournal of Statistical Software, 2011
We introduce a pathwise algorithm for the Cox proportional hazards model, regularized by convex combinations of ℓ1 and ℓ2 penalties (elastic net). Our algorithm fits via cyclical coordinate descent, and employs warm starts to find a solution along a ...
N. Simon   +3 more
semanticscholar   +1 more source

Generating Survival Times to Simulate Cox Proportional Hazards Models [PDF]

open access: yes, 2003
This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression ...
Augustin, Thomas   +2 more
core   +2 more sources

Statistical estimation in the proportional hazards model with risk set sampling [PDF]

open access: yes, 2004
Thomas' partial likelihood estimator of regression parameters is widely used in the analysis of nested case-control data with Cox's model. This paper proposes a new estimator of the regression parameters, which is consistent and asymptotically normal ...
Chen, Kani
core   +2 more sources

Bayesian semiparametric inference for multivariate doubly-interval-censored data [PDF]

open access: yes, 2010
Based on a data set obtained in a dental longitudinal study, conducted in Flanders (Belgium), the joint time to caries distribution of permanent first molars was modeled as a function of covariates.
De Iorio, Maria   +3 more
core   +4 more sources

An Online Updating Approach for Testing the Proportional Hazards Assumption with Streams of Big Survival Data

open access: yes, 2018
The Cox model, which remains as the first choice in analyzing time-to-event data even for large datasets, relies on the proportional hazards assumption. When the data size exceeds the computer memory, the standard statistics for testing the proportional ...
Schifano, Elizabeth D.   +3 more
core   +1 more source

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