Regularization for Cox's proportional hazards model with NP-dimensionality
High throughput genetic sequencing arrays with thousands of measurements per sample and a great amount of related censored clinical data have increased demanding need for better measurement specific model selection.
Bradic, Jelena+2 more
core +2 more sources
Proportional hazards models with discrete frailty [PDF]
We extend proportional hazards frailty models for lifetime data to allow a negative binomial, Poisson, Geometric or other discrete distribution of the frailty variable. This might represent, for example, the unknown number of flaws in an item under test.
Caroni, Chrys+2 more
openaire +5 more sources
Accurate training of the Cox proportional hazards model on vertically-partitioned data while preserving privacy [PDF]
Background Analysing distributed medical data is challenging because of data sensitivity and various regulations to access and combine data. Some privacy-preserving methods are known for analyzing horizontally-partitioned data, where different ...
Bart Kamphorst+4 more
doaj +2 more sources
Causal Interactions in the Proportional Hazards Model [PDF]
The paper relates estimation and testing for additive interaction in proportional hazards models to causal interactions within the counterfactual framework. A definition of a causal interaction for time-to-event outcomes is given that generalizes existing definitions for dichotomous outcomes. Conditions are given concerning the relative excess risk due
Tyler J. VanderWeele
openaire +4 more sources
Reasons why osteoarthritis predicts mortality: path analysis within a Cox proportional hazards model [PDF]
Objectives To identify potentially modifiable factors that mediate the association between symptomatic osteoarthritis (OA) and premature mortality.Methods A population-based prospective cohort study; primary care medical record data were linked to self ...
George Peat+7 more
doaj +2 more sources
Limitations of applying the COX proportional hazards model to glioma studies [PDF]
Jihao Xue+6 more
doaj +2 more sources
Does the Tax Cuts Policy Lower Firm Survival Risk? Evidence from China [PDF]
This paper examines the effect of tax cuts policy on firm survival risk. We analyze a panel data of China’s listed companies over the period 20082021 based on two different techniques: Kaplan-Meier survival estimator and the Cox proportional hazards ...
Wang Hong+3 more
doaj +1 more source
Using Wavelet Shrinkage in the Cox Proportional Hazards Regression model (simulation study) [PDF]
The proposed method in this paper dealt with the problem of data contamination in the Cox Proportional Hazards Regression model (CPHRM) by using Wavelet Shrinkage to de-noise data, calculating the discrete wavelet transformation coefficients for wavelets
taha ali, Jwana Rostam Qadir
doaj +1 more source
Comparison of regression imputation methods of baseline covariates that predict survival outcomes
Introduction: Missing data are inevitable in medical research and appropriate handling of missing data is critical for statistical estimation and making inferences.
Nicole Solomon+2 more
doaj +1 more source
Identification of a competing risks model with unknown transformations of latent failure times [PDF]
This paper is concerned with identification of a competing risks model with unknown transformations of latent failure times. The model in this paper includes, as special cases, competing risks versions of proportional hazards, mixed proportional ...
Lee, S.
core +8 more sources