Results 71 to 80 of about 800,848 (376)

Efficient Estimation and Inference in the Proportional Odds Model for Survival Data

open access: yesMathematics, 2022
In modeling time-to-event data with long-term survivors, the proportional hazards model is widely used for its easy and direct interpretation as well as the flexibility to accommodate the past information and allow time-varying predictors.
Xifen Huang   +4 more
doaj   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

Estimation of treatment effects in weighted log-rank tests

open access: yesContemporary Clinical Trials Communications, 2017
Non-proportional hazards have been observed in clinical trials. The log-rank test loses power and the standard Cox model generally produces biased estimates under such conditions.
Ray S. Lin, Larry F. León
doaj   +1 more source

An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect [PDF]

open access: yes, 2014
Background: Most randomized controlled trials with a time-to-event outcome are designed and analysed under the proportional hazards assumption, with a target hazard ratio for the treatment effect in mind. However, the hazards may be non-proportional.
D Stark   +14 more
core   +2 more sources

Relaxing the independent censoring assumption in the Cox proportional hazards model using multiple imputation

open access: yesStatistics in Medicine, 2014
The Cox proportional hazards model is frequently used in medical statistics. The standard methods for fitting this model rely on the assumption of independent censoring.

semanticscholar   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül   +2 more
wiley   +1 more source

A semiparametric Bayesian proportional hazards model for interval censored data with frailty effects

open access: yesBMC Medical Research Methodology, 2009
Background Multivariate analysis of interval censored event data based on classical likelihood methods is notoriously cumbersome. Likelihood inference for models which additionally include random effects are not available at all.
Hölzel Dieter   +3 more
doaj   +1 more source

Attributable Risk Function in the Proportional Hazards Model [PDF]

open access: yes, 2005
As an epidemiological parameter, the population attributable fraction is an important measure to quantify the public health attributable risk of an exposure to morbidity and mortality.
Chen, Ying Qing   +2 more
core   +1 more source

Modeling county level breast cancer survival data using a covariate-adjusted frailty proportional hazards model

open access: yes, 2015
Understanding the factors that explain differences in survival times is an important issue for establishing policies to improve national health systems.
Hanson, Timothy   +3 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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