Results 71 to 80 of about 786,239 (293)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Nonparametric Regression in Proportional Hazards Models

open access: yesJOURNAL OF THE JAPAN STATISTICAL SOCIETY, 2004
Summary: \textit{J. Fan} et al. [Ann. Stat. 25, No. 4, 1661--1690 (1997; Zbl 0890.62023)] considered two kinds of nonparametric estimators of the effects of the covariates in proportional hazards models. One of them has no parametric assumption on the baseline hazard function and is based on the integration of the estimated first order derivative of ...
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

A proportional hazards model of bank failure: an examination of its usefulness as an early warning tool [PDF]

open access: yes
An explanation of how a Cox proportional hazards model can be used to identify both failed and healthy banks with a high degree of accuracy using a relatively small set of publicly available data.Bank ...
Gary Whalen
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Recovery of the Baseline Incidence Density in Censored Time-to-Event Analysis [PDF]

open access: yes, 2010
Time-to-event analyses are often concerned with the effects of explanatory factors on the underlying incidence density, but since there is no intrinsic interest in the form of the incidence density itself, a proportional hazards model is used. When part
Aickin, Mikel
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Proportional Asymptotics of Piecewise Exponential Proportional Hazards Models

open access: yes
We study the flexible piecewise exponential model in a high dimensional setting where the number of covariates $p$ grows proportionally to the number of observations $n$ and under the hypothesis of random uncorrelated Gaussian designs. We prove rigorously that the optimal ridge penalized log-likelihood of the model converges in probability to the ...
openaire   +2 more sources

The Duration of Trade Revisited: Continuous-Time vs. Discrete-Time Hazards [PDF]

open access: yes
The recent literature on the duration of trade has predominantly analyzed the determinants of trade flow durations using Cox proportional hazards models.
Hess, Wolfgang, Persson, Maria
core  

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