Detecting prognostic biomarkers of breast cancer by regularized Cox proportional hazards models [PDF]
Journal of Translational Medicine, 2021 Background The successful identification of breast cancer (BRCA) prognostic biomarkers is essential for the strategic interference of BRCA patients.
Lingyu Li, Zhi-Ping Liu
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Efficient Post-Shrinkage Estimation Strategies in High-Dimensional Cox’s Proportional Hazards Models [PDF]
EntropyRegularization methods such as LASSO, adaptive LASSO, Elastic-Net, and SCAD are widely employed for variable selection in statistical modeling. However, these methods primarily focus on variables with strong effects while often overlooking weaker signals,
Syed Ejaz Ahmed +2 more
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BHCox: Bayesian heredity-constrained Cox proportional hazards models for detecting gene-environment interactions [PDF]
BMC BioinformaticsBackground Gene-environment (G × E) interactions play a critical role in understanding the etiology of diseases and exploring the factors that affect disease prognosis.
Na Sun +6 more
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On hazard ratio estimators by proportional hazards models in matched-pair cohort studies [PDF]
Emerging Themes in Epidemiology, 2017 Background In matched-pair cohort studies with censored events, the hazard ratio (HR) may be of main interest. However, it is lesser known in epidemiologic literature that the partial maximum likelihood estimator of a common HR conditional on matched ...
Tomohiro Shinozaki +2 more
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Mediation Analysis with Survival Outcomes: Accelerated Failure Time Versus Proportional Hazards Models [PDF]
Frontiers in Psychology, 2016 Objective: Survival time is an important type of outcome variable in treatment research. Currently, limited guidance is available regarding performing mediation analyses with survival outcomes, which generally do not have normally distributed errors, and
Lois A Gelfand +3 more
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Pain and mortality among older adults in Korea [PDF]
Epidemiology and Health, 2021 OBJECTIVES With the increasing elderly population with chronic disease, understanding pain and designing appropriate policy interventions to it have become crucial.
Chiil Song, Wankyo Chung
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Frontiers in Pharmacology, 2022 Objective: Intraplaque neovascularization is a marker of plaque vulnerability and is used to predict the risk of future vascular events in patients with symptomatic carotid stenosis; however, its association with asymptomatic carotid stenosis has not ...
Liuping Cui +10 more
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The Southern European Atlantic Diet and all-cause mortality in older adults
BMC Medicine, 2021 Background The Southern European Atlantic Diet (SEAD) is the traditional diet of Northern Portugal and North-Western Spain. Higher adherence to the SEAD has been associated with lower levels of some cardiovascular risk factors and reduced risk for ...
Adrián Carballo-Casla +7 more
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Does Atrial Fibrillation Increase the Risk of New Onset Myocardial Infarction? [PDF]
Zhongguo quanke yixue, 2022 Background Atrial fibrillation is the most obvious arrhythmia in medical practice. Atrial fibrillation has been listed as one of the eight fastest-growing causes of death since 1990.
Yujing HAO, Jie YU, Quanle HAN, Ruiying MAO, Jing YU, Lihua SONG, Shouling WU
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Three-year Survival of Women with Breast Cancer in Basrah, Iraq
Oman Medical Journal, 2020 Objectives: We sought to determine the overall observed three-year survival rate of women with breast cancer in Basrah, Iraq, and investigate the associated factors. Methods: Data was collected retrospectively from the Oncology Center registry in Basrah,
Jasim N. Al-Asadi, Sundus M. Al-Mayah
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