Results 71 to 80 of about 106,408 (283)

Multiaxial Low Cycle Fatigue of 1070Aluminum under Stress Controlled Non-proportional Loading [PDF]

open access: yes, 2007
This paper describes the low cycle fatigue life of 1070 aluminum under stress controlled multiaxial loading. Proportional loading tests were carried out under combined push-pull and reversed torsion.
伊藤, 隆基   +5 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Experimental fracture characterisation of an anisotropic magnesium alloy sheet in proportional and non-proportional loading conditions [PDF]

open access: yes, 2018
The final publication is available at Elsevier via http://dx.doi.org/10.1016/j.ijsolstr.2018.04.010. © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/A comprehensive ...
Worswick, Michael J.   +5 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Fatigue Testing and Evaluation of Fatigue Strength under Multiaxial Stress State; Why do we need fatigue testing?

open access: yesMATEC Web of Conferences, 2018
Types of multiaxial fatigue tests and their experimental results are presented in this paper. There are typical three types in multiaxial fatigue tests: the combining push-pull and reversed torsion loading test using hollow cylinder specimen, the biaxial
Itoh Takamoto   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Application of Electrohydraulic Proportional Technology in Mill Loading System

open access: yes, 2011
The paper designs electrohydraulic proportional loading system which meets the adaptive requirements of variable loading for the system by analyzing the structure and the theory of mill loading system.
Aai Jun Li   +4 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Experimental Study on Closed Loop Simulated Loading of Proportional Relief Valve

open access: yesChemical Engineering Transactions, 2015
Proportional relief valve is usually used in the hydraulic experimental platform to simulate the load. The open- loop simulated loading has the characteristics of exiting steady-state error and control accuracy easily being affected by the flow ...
Y. Liu, B. Yang, Z.S. Wu, M. Chen
doaj   +1 more source

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