Results 41 to 50 of about 25,996 (287)

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Students Proportional Reasoning Level in Solving Ill Structured Problem on Proportion Material in Terms of Gregorc’s Thinking Style

Journal of Medives: Journal of Mathematics Education IKIP Veteran Semarang
This study examines the level of proportional reasoning in students when solving ill-structured problems concerning proportions, in terms of Gregorc's cognitive styles.
Yasmine Az Zahra Awwalina Pramono, Abdussakir Abdussakir, Wahyu Henky Irawan, Imam Sujarwo   +3 more
doaj   +1 more source

Research Findings' Impact on the Representation of Proportional Reasoning in Swedish Mathematics Textbooks

REDIMAT, 2016
This article investigates the impact of research findings on the representation of proportional reasoning in two commonly used Swedish mathematics textbook series for grades 7-9.
Linda Marie Ahl
doaj   +1 more source

PACE Technique to Error Categories: Its Effectiveness in Improving Word Problem Performance in Mathematics among the 7th Grade Students

Qubahan Academic Journal, 2023
This research determined the effectiveness of the PACE (Present the error, Analyze the error, Correct the Error, Explain the error) technique in improving the mathematics performance in solving word problems among 7th Grade students in Harnett Central ...
Roghene A. Coloma, Florante P. Ibarra, Amirul Mukminin, Lenny Marzulina, Herri Mulyono, Kasinyo Harto   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Identifikasi Kemampuan Berpikir Logis Mahasiswa Calon Guru Fisika Menggunakan Instrument TOLT

JPFT (Jurnal Pendidikan Fisika dan Teknologi), 2021
This study aimed to identify the type of reasoning and the level of prospective physics teacher students’ logical thinking ability. This type of research was a field study with a quantitative descriptive method.
Rahmawati Rahmawati, Edy Kurniawan, A. Muafiah Nur   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Wald Test Formulations in DIF Detection of CDM Data with the Proportional Reasoning Test

International Journal of Assessment Tools in Education, 2020
This study aims to conduct differential item functioning analyses in the context of cognitive diagnosis assessments using various formulations of the Wald test. In implementing the Wald test, two scenarios are considered: one where the underlying reduced
Ragıp Terzi, Jimmy De La Torre, Likun Hou   +2 more
doaj   +1 more source