Results 91 to 100 of about 77,060 (292)

Proportionality: a valid alternative to correlation for relative data [PDF]

open access: yes, 2015
In the life sciences, many measurement methods yield only the relative abundances of different components in a sample. With such relative-or compositional-data, differential expression needs careful interpretation, and correlation-a statistical workhorse
Lovell David   +21 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Verhältnismäßigkeitsgrundsatz und Gewaltenteilung: The Relationship Between the Principle of Proportionality and the Separation of Powers in the German Legal System [PDF]

open access: yes
reservedLa presente tesi si concentra sulla relazione tra due principi fondamentali dell’ordinamento giuridico tedesco, il principio di proporzionalità (Verhältnismäßigkeitsgrundsatz) e la separazione dei poteri (Gewaltenteilung).
MARIGONDA, FEDERICA
core  

Proportionality and Judicial Activism [PDF]

open access: yes, 2017
The principle of proportionality is currently one of the most discussed topics in the field of comparative constitutional law. Many critics claim that courts use the proportionality test as an instrument of judicial self-empowerment.
Petersen, Niels,, Niels Petersen
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Appropriateness of the Obligation Writ not to leave the House or Place of Residence under Electronic Monitoring with the Individual Freedom of the Accused in French and Iranian Law [PDF]

open access: yesپژوهش های حقوق تطبیقی
After the scientists of Harvard University in collaboration with a group of researchers of this university invented a type of electronic monitoring technology, the attention of criminal law scientists in European countries was drawn to this monitoring ...
Mohammad Jafar Habibzadeh, Adnan Qasem,
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

A Simple Test for the Absence of Covariate Dependence in Hazard Regression Models [PDF]

open access: yes, 2004
This paper extends commonly used tests for equality of hazard rates in a two-sample or k-sample setup to a situation where the covariate under study is continuous.
Bhattacharjee, Arnab   +3 more
core  

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