Results 81 to 90 of about 95,447 (283)

Local Meanings of Proportionality

open access: yes, 2021
Proportionality increasingly dominates legal imagination. Initially conceived of as a principle that regulates police action, today it is progressively established as an advanced tool of liberal constitutional science. Its spread, accompanied by a global
MARKETOU, Afroditi
core   +2 more sources

Appropriateness of the Obligation Writ not to leave the House or Place of Residence under Electronic Monitoring with the Individual Freedom of the Accused in French and Iranian Law [PDF]

open access: yesپژوهش های حقوق تطبیقی
After the scientists of Harvard University in collaboration with a group of researchers of this university invented a type of electronic monitoring technology, the attention of criminal law scientists in European countries was drawn to this monitoring ...
Mohammad Jafar Habibzadeh, Adnan Qasem,
doaj  

Two Forms of Proportionality. Substantive and Institutional

open access: yes
The essay draws and develops a distinction between two forms that the standard of proportionality can take: substantive proportionality and institutional proportionality.
C. Caruso, C. Valentini
core   +1 more source

Turning proportionality upside down: from legitimising principle to critical tool

open access: yes, 2019
The reconstruction and analysis of the case law of the European Court of Justice of the European Union (ECJ) provides new insights into the structure and the normative implications of proportionality as a tool of judicial decision-making.
Menéndez Menéndez, Agustín José   +1 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Improvment of Clothes Fit for Different Female Bodies

open access: yesAUTEX Research Journal, 2017
The factors influencing for fit and suit of women’s clothing have been studied. The main reason of misfit is the nonconformity between the front and back width of pattern block, the corresponding body sizes taken across the hipline, and the textile ...
Surikova Olga V.   +2 more
doaj   +1 more source

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