Results 61 to 70 of about 92,736 (272)

Conceptualising Proportionality and Criminal Sanctions in EU Law : Three Different Visions [PDF]

open access: yes
The principle of proportionality is a key principle in EU law; however, it has distinctive meanings in different contexts. In the field of free movement, proportionality constrains the Member States’ possibilities to diverge from EU law on the basis of ...
Öberg, Jacob; id_orcid   +2 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Proportionality in the conduct of hostilities : the incidental harm side of proportionality assessments [PDF]

open access: yes, 2018
Published online on 01 December 2018Military operations are taking place with increasing frequency in densely populated areas. Such operations result in loss of life and harm to civilians, as well as damage to civilian objects, (including infrastructure ...
GILLARD, Emanuela-Chiara
core   +1 more source

THE PRINCIPLE OF PROPORTIONALITY, THE IMPLEMENTATION OF EU LAW, THE PUBLIC ADMINISTRATION. GENERAL AND PRELIMINARY ASPECTS [PDF]

open access: yesChallenges of the Knowledge Society, 2019
Fundamental principle of EU law is governed, at present, by Article 5 (4) of the EU Treaty, as well as Article 5 from the Protocol no 2 of the Lisbon Treaty, the Protocol on the application of the principle of subsidiarity and proportionality.
Oana ŞARAMET
doaj  

La restricción de los derechos fundamentales : un concepto en evolución y su fundamento constitucional

open access: yesRevista de Derecho Político, 2010
El concepto de «restricción de los Derechos Fundamentales» presenta una extraordinaria utilidad para el campo del Derecho Procesal. Esta circunstancia se pone de relieve a la hora de precisar las exigencias constitucionales que han de cumplir aquellos ...
María José Cabezudo Bajo
doaj   +1 more source

Partial Orders with Respect to Continuous Covariates and Tests for the Proportional Hazards Model [PDF]

open access: yes, 2008
Several omnibus tests of the proportional hazards assumption have been proposed in the literature. In the two-sample case, tests have also been developed against ordered alternatives like monotone hazard ratio and monotone ratio of cumulative hazards ...
Bhattacharjee, Arnab   +1 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

A disposição física da Sala de Audiências: a proximidade dos Membros do Poder Judiciário e do Ministério Público e seus reflexos sobre o devido Processo Legal

open access: yesRevista Interdisciplinar de Direito, 2015
The present study seeks to analyze the unconstitutionality of Article 18, I, “a” of Supplementary Law nº 75/93 and Article 41, Clause XI of the Law 8.625 / 1993.
Márcia Berião César
doaj  

The Value of Behavioral Economics for EU Judicial Decision-Making

open access: yesGerman Law Journal, 2020
This Article analyzes the value of behavioral economics for EU judicial decision-making. The first part introduces the foundations of behavioral economics by focusing on cognitive illusions, prospect theory, and the underlying distinction between ...
Christoph K. Winter
doaj   +1 more source

Home - About - Disclaimer - Privacy