Results 61 to 70 of about 341,991 (271)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Subsidiarity and Proportionality in the Single Market: An EU fit for inclusive growth [PDF]

open access: yes, 2018
This report offers a fresh perspective on the principles of subsidiarity and proportionality in the European Union based on a thorough-going economic analysis.
Jensen, Jonas Bjarke   +1 more
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Protection of civilian objects during armed conflicts

open access: yesНауковий вісник Ужгородського національного університету. Серія Право
This article explores the international legal mechanisms designed to shield civilian objects from harm during armed hostilities, focusing on international humanitarian law (IHL) provisions.
S.S. Korol’ov   +2 more
doaj   +1 more source

THE PRINCIPLE OF PROPORTIONALITY, THE IMPLEMENTATION OF EU LAW, THE PUBLIC ADMINISTRATION. GENERAL AND PRELIMINARY ASPECTS [PDF]

open access: yesChallenges of the Knowledge Society, 2019
Fundamental principle of EU law is governed, at present, by Article 5 (4) of the EU Treaty, as well as Article 5 from the Protocol no 2 of the Lisbon Treaty, the Protocol on the application of the principle of subsidiarity and proportionality.
Oana ŞARAMET
doaj  

La restricción de los derechos fundamentales : un concepto en evolución y su fundamento constitucional

open access: yesRevista de Derecho Político, 2010
El concepto de «restricción de los Derechos Fundamentales» presenta una extraordinaria utilidad para el campo del Derecho Procesal. Esta circunstancia se pone de relieve a la hora de precisar las exigencias constitucionales que han de cumplir aquellos ...
María José Cabezudo Bajo
doaj   +1 more source

Technological Innovations and International Humanitarian Law: Challenges and Tensions [PDF]

open access: yesPolish Political Science Yearbook, 2017
In recent years, armed conflicts have changed in nature (civil war, ‘terrorism’) and the means used are increasingly technological (robotisation, cyberwar). Faced with these developments, some would claim International Humanitarian Law (IHL) is outdated.
Eric Pomès
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Fair and Square: Cake-Cutting in Two Dimensions

open access: yes, 2017
We consider the classic problem of fairly dividing a heterogeneous good ("cake") among several agents with different valuations. Classic cake-cutting procedures either allocate each agent a collection of disconnected pieces, or assume that the cake is a ...
Aumann, Yonatan   +3 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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