Results 71 to 80 of about 76,716 (294)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

A disposição física da Sala de Audiências: a proximidade dos Membros do Poder Judiciário e do Ministério Público e seus reflexos sobre o devido Processo Legal

open access: yesRevista Interdisciplinar de Direito, 2015
The present study seeks to analyze the unconstitutionality of Article 18, I, “a” of Supplementary Law nº 75/93 and Article 41, Clause XI of the Law 8.625 / 1993.
Márcia Berião César
doaj  

Proportionality and Its Alternatives [PDF]

open access: yes, 2020
This article examines the claim that the adoption of structured proportionality analysis is not well suited to the Australian constitutional context and argues that this claim is mistaken.
Stone, Adrienne
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Protection of civilian objects during armed conflicts

open access: yesНауковий вісник Ужгородського національного університету. Серія Право
This article explores the international legal mechanisms designed to shield civilian objects from harm during armed hostilities, focusing on international humanitarian law (IHL) provisions.
S.S. Korol’ov   +2 more
doaj   +1 more source

THE PRINCIPLE OF PROPORTIONALITY, THE IMPLEMENTATION OF EU LAW, THE PUBLIC ADMINISTRATION. GENERAL AND PRELIMINARY ASPECTS [PDF]

open access: yesChallenges of the Knowledge Society, 2019
Fundamental principle of EU law is governed, at present, by Article 5 (4) of the EU Treaty, as well as Article 5 from the Protocol no 2 of the Lisbon Treaty, the Protocol on the application of the principle of subsidiarity and proportionality.
Oana ŞARAMET
doaj  

La restricción de los derechos fundamentales : un concepto en evolución y su fundamento constitucional

open access: yesRevista de Derecho Político, 2010
El concepto de «restricción de los Derechos Fundamentales» presenta una extraordinaria utilidad para el campo del Derecho Procesal. Esta circunstancia se pone de relieve a la hora de precisar las exigencias constitucionales que han de cumplir aquellos ...
María José Cabezudo Bajo
doaj   +1 more source

Technological Innovations and International Humanitarian Law: Challenges and Tensions [PDF]

open access: yesPolish Political Science Yearbook, 2017
In recent years, armed conflicts have changed in nature (civil war, ‘terrorism’) and the means used are increasingly technological (robotisation, cyberwar). Faced with these developments, some would claim International Humanitarian Law (IHL) is outdated.
Eric Pomès
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Two Forms of Proportionality. Substantive and Institutional

open access: yes
The essay draws and develops a distinction between two forms that the standard of proportionality can take: substantive proportionality and institutional proportionality.
C. Caruso, C. Valentini
core   +1 more source

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