Results 51 to 60 of about 77,060 (292)

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel   +15 more
wiley   +1 more source

Modeling the Patterns of Civil Confiscation: Balancing Effectiveness, Proportionality and the Right to Be Presumed Innocent

open access: yesBaltic Journal of Law & Politics, 2020
This article elaborates on recent developments in modelling the advanced measure for prevention of organized and serious criminality and corruption – civil confiscation.
Bikelis Skirmantas
doaj   +1 more source

Introduction: Redressing EU law, Redress through EU law?

open access: yesEuropean Law Open, 2023
This short introduction to the symposium on Christodoulidis’s The Redress of Law highlights the reasons why the book will be relevant to readers interested in EU law.
Agustín José Menéndez
doaj   +1 more source

Proportionality and precaution

open access: yesGlobal Constitutionalism
Abstract During the COVID-19 pandemic, governments worldwide invoked the ‘precautionary principle’ to justify policies designed to protect public health. This principle holds that the state may act proactively to avert harm where there is factual uncertainty about that harm and the efficacy of policies proposed to
Mark Friedman, Anthony Sangiuliano
openaire   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

The Principle of Proportionality in International Law: Foundations and Variations [PDF]

open access: yes, 2017
Originally based upon the principle of equity, proportionality is predominantly used in the field of human rights protection, the use of force and countermeasures, humanitarian law, maritime boundary law, trade law and investment protection.
Rachel Liechti-McKee   +9 more
core   +1 more source

Proportionality in Practice: Quantifying Proportionality in Ordinal Elections

open access: yesCoRR
Proportional representation plays a crucial role in electoral systems. In ordinal elections, where voters rank candidates based on their preferences, the Single Transferable Vote (STV) is the most widely used proportional voting method. STV is considered proportional because it satisfies an axiom requiring that large enough solid coalitions of voters ...
Tuva Bardal   +3 more
openaire   +2 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Conceptualising Proportionality and Criminal Sanctions in EU Law : Three Different Visions [PDF]

open access: yes
The principle of proportionality is a key principle in EU law; however, it has distinctive meanings in different contexts. In the field of free movement, proportionality constrains the Member States’ possibilities to diverge from EU law on the basis of ...
Öberg, Jacob; id_orcid   +2 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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