Results 111 to 120 of about 111,297 (312)

Effectiveness of galcanezumab versus topiramate, amitriptyline, and other select traditional oral migraine preventives with evidence of efficacy: 3‐Month results from the TRIUMPH study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To compare the 3‐month effectiveness of galcanezumab with select traditional oral migraine preventive (TOMP) medications recommended by scientific societies (TOMP efficacy subset) and with the most frequently used individual TOMP medications.
Shivang Joshi, Cristina Tassorelli, Manjit Matharu, Taoufik Alsaadi, Carlos Vallarino, Lars Viktrup, Maurice Vincent, Rebecca L. Robinson   +7 more
wiley   +1 more source

Retrospective Evaluation of an Oral Propranolol Delivery Strategy in 25 Cases of Infantile Hemangioma

Journal of Plastic and Reconstructive Surgery
Objectives: The majority of infantile hemangiomas shrink on their own, but when there is a chance of functional impairment, ulceration, or aesthetic issues, an active therapeutic intervention is needed.
Shinichi Ashizawa, Takanobu Kan, Shunsuke Takahagi, Mikio Kawai, Sayuri Toda, Yasumasa Iwasaki, Shuhei Karakawa, Michihiro Hide, Akio Tanaka   +8 more
doaj  

Suzetrigine as a novel treatment for headache disorders: A case series

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Suzetrigine is a selective voltage‐gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients refractory to standard treatments in an ...
Molly Fensterwald, Jordan Johnson, Angel Moreno, Shawn Conger‐Love, Charles Flippen, Chelsea Hesterman, Mollie Johnston, Joshua Kamins, Karla Minota, Peony Pak, Salman Hashim, Thanh‐Liem Huynh‐Tran, Noelle Kobayashi, Bradley Shane, Andrew Charles, Sinifunanya Nwaobi   +15 more
wiley   +1 more source

Pharmaceuticals in the aquatic environment: β-blockers as a case study

, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 20/09/2008.The presence of many human pharmaceuticals in the aquatic environment is now a worldwide concern and yet little is known of the chronic effects ...
Giltrow, Emma
core  

R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

eLife, 2019
Propranolol is an approved non-selective β-adrenergic blocker that is first line therapy for infantile hemangioma. Despite the clinical benefit of propranolol therapy in hemangioma, the mechanistic understanding of what drives this outcome is limited ...
Jeroen Overman, Frank Fontaine, Jill Wylie-Sears, Mehdi Moustaqil, Lan Huang, Marie Meurer, Ivy Kim Chiang, Emmanuelle Lesieur, Jatin Patel, Johannes Zuegg, Eddy Pasquier, Emma Sierecki, Yann Gambin, Mohamed Hamdan, Kiarash Khosrotehrani, Gregor Andelfinger, Joyce Bischoff, Mathias Francois   +17 more
doaj   +1 more source

Propranolol in pregnancy three year prospective study

, 1983
We compared propranolol with methyldopa in a randomized prospective study of 28 women with pregnancy associated hypertension. Both drugs were equally effective in controlling maternal hypertension.
Craswell P.W., Livingstone I., Smith M.T., Bevan E.B., Eadie M.J.   +4 more
core   +1 more source

Effects of candesartan and propranolol combination therapy versus propranolol monotherapy in reducing portal hypertension [PDF]

, 2014
Background/AimsAngiotensin receptor blockers (ARBs) inhibit activated hepatic stellate cell contraction and are thought to reduce the dynamic portion of intrahepatic resistance.
Sang Ok Kwon, Jung Min Kim, Youn Zoo Cho, Soon Koo Baik, Ji Hoon Na, Hye Won Kang, Young Ju Kim, Seung Hwan Cha, Hyun Sik Kim, Hyoun A Kim, Moon Young Kim, Jae Hyun Kim   +11 more
core   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

International Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota, Klaus Kümmerer, Isabel Martins de Almeida, Emília Sousa   +3 more
wiley   +1 more source

Using a NanoBRET-Based Ligand-Binding Assay at the β₂-Adrenoceptor for Undergraduate Pharmacology Education. [PDF]

Pharmacol Res Perspect
ABSTRACT The teaching of pharmacology includes a fundamental understanding of ligand binding; how it is measured and how it is calculated. We sought to modernize the techniques by which ligand affinity is determined by undergraduate students and introduce them to parameter estimation through curve fitting.
Pearce A, Huang X, Redfern-Nichols T, Sisk CM, Safitri D, Collins M, Malcharek MA, García ST, Nakamura C, Harris A, Ladds G.   +10 more
europepmc   +2 more sources

Propranolol attenuates hemorrhage and accelerates wound healing in severely burned adults

Critical Care, 2015
IntroductionPropranolol, a nonselective β-blocker, exerts an indirect effect on the vasculature by leaving α-adrenergic receptors unopposed, resulting in peripheral vasoconstriction.
Arham Ali, D. Herndon, Ashish Mamachen, Samir Hasan, C. Andersen, Ro-Jon Grogans, Jordan L. Brewer, Jong O. Lee, Jamie M. Heffernan, O. Suman, C. Finnerty   +10 more
semanticscholar   +1 more source