Results 111 to 120 of about 41,520 (219)

Struktureller Mechanismus eines Aktivitäts‐Photoschalters am β2‐adrenergen Rezeptor

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Zeitaufgelöste Strukturen aus Messungen an Röntgen‐Freie‐Elektronen‐Lasern in Kombination mit zellulären Assays zeigen, wie der photoschaltbare β‐Blocker Photoazolol‐1 als Wirksamkeits‐Photoschalter der Funktion des β2‐adrenergen Rezeptor wirkt. Die lichtinduzierte Neupositionierung des Liganden verschiebt die Aktivität von inversem Agonistimus hin zu ...
Robin Stipp   +29 more
wiley   +1 more source

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 18, 27 April 2026.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp   +29 more
wiley   +1 more source

Beta Blocker Intoxications in Belgium: A Data Analysis with Focus on Propranolol. [PDF]

open access: yesPharmacy (Basel)
van den Boogaard B   +5 more
europepmc   +1 more source

PHACE syndrome: report of five cases. [PDF]

open access: yesAn Bras Dermatol
de Oliveira Neumayer JM   +5 more
europepmc   +1 more source

Clinical predictors of propranolol responsiveness in pediatric migraine: a prospective observational study. [PDF]

open access: yesJ Oral Facial Pain Headache
Baykan M   +4 more
europepmc   +1 more source

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