Results 91 to 100 of about 42,221 (227)

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

On the History of Hepatic Vein Catheterization

open access: yesLiver International, Volume 46, Issue 9, September 2026.
ABSTRACT Hepatic vein catheterization (HVC) in man was first performed 80 years ago in the wake of right‐sided heart catheterization. Several new methods, recognitions and concepts followed, especially the indirect Fick‐method for determination of splanchnic blood flow. Five years passed before pressure measurements were performed and routine HVCs were
Jens Henrik Henriksen   +2 more
wiley   +1 more source

Understanding CPVT pathogenic mechanisms based on mutation location within RyR2: towards personalized medicine?

open access: yes
The Journal of Physiology, EarlyView.
Jean‐Pierre Benitah   +2 more
wiley   +1 more source

Exploiting the Reverse Function of Ene‐Reductase Enzymes in the Continuous Flow Synthesis of Naphthols From Tetralones

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.
The development and optimization of a continuous flow method for the use of ERED enzymes in the reverse mode is presented to convert tetralones into naphthols using air as the terminal oxidant. Both solution‐phase and the immobilized enzyme were explored along with different reactor configurations leading to product yields of up to 83% in short ...
Ruairí Bannon   +6 more
wiley   +1 more source

Intranasal Administration of Isoeugenol Improves Memory Deficits in APP/PS1 Old Mice—A Role Beyond Nrf2 Activation?

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Inactivation of the Nrf2/Are pathway in AD leads to decreased antioxidant and anti‐inflammatory response and to the accumulation of beta‐amyloid (Aβ) plaques, resulting in cognitive failure. Treatment with Isoeugenol activates Nrf2, reversing these outcomes by promoting antioxidant response in neuronal cells (N2a) and by increasing the anti ...
Ana Silva   +14 more
wiley   +1 more source

Optimized SPE‐HPLC‐FLD Method for the Simultaneous Determination of Olaparib, Propranolol, and Furosemide in Human Urine

open access: yesBiomedical Chromatography, Volume 40, Issue 8, August 2026.
ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris   +2 more
wiley   +1 more source

Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti‐mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow‐up for ...
Ali Gohar   +9 more
wiley   +1 more source

Midterm Efficacy of SubcutAneous Implantable CardioVErter‐Defibrillator in ≤ 18 Year‐Old CHILDREN (SAVE CHILDREN‐II Registry)

open access: yesJournal of Arrhythmia, Volume 42, Issue 4, August 2026.
S‐ICD therapy demonstrated favorable mid‐term safety and efficacy in pediatric patients, with durable sensing performance and a low incidence of device‐related infection. ABSTRACT Background The subcutaneous implantable cardioverter‐defibrillator (S‐ICD) avoids transvenous leads and is a promising option for sudden cardiac death (SCD) prevention in ...
Hitoshi Mori   +76 more
wiley   +1 more source

Bisoprolol Treatment and Adherence in Pediatric Patients With Genotype‐Positive Long QT Syndrome

open access: yesJournal of Arrhythmia, Volume 42, Issue 4, August 2026.
LQTS is commonly treated with non‐selective beta‐blockers. In this study on Finnish pediatric patients with genotype positive LQTS1 or LQTS2, most with a Finnish founder mutation, the beta‐1‐selective bisoprolol was the most commonly used beta‐blocker with good adherence, effective heart rate control, and no cardiac events observed during follow‐up ...
Eemil Taipalus   +4 more
wiley   +1 more source

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