Results 81 to 90 of about 42,221 (227)
Lower limb blood flow responses during higher‐ and lower‐load bilateral leg press exercise
Experimental Physiology, EarlyView.Abstract The local blood flow response to resistance exercise (RE) is complicated by local muscular contractions and large swings in perfusion pressure. The magnitude of these responses might vary according to exercise intensity, number of sets and number of repetitions, and as a result, the local shear environment during RE remains uncharacterized. We
Eudoxia Zafiris +3 more
wiley +1 more source
Repolarization adaptation to rapid change in heart rate in human models – a review
The Journal of Physiology, EarlyView.Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt +5 more
wiley +1 more source
A case of propylthiouracil induced antineutrophil cytoplasmic antibody associated vasculopathy
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Nikhil Dwivedi +2 more
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
The Journal of Physiology, EarlyView.Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
Mechanisms reducing parasympathetic activity in chronic hypoxia
The Journal of Physiology, EarlyView.Abstract figure legend Parasympathetic activity is reduced in chronic hypoxia, but the underlying mechanism(s) are unclear. Using β‐adrenergic blockade to isolate parasympathetic control of heart rate at sea level and after 9‐12 days at high altitude, we investigated whether (i) chemoreflex activation, (ii) increased pulmonary ventilation and/or (iii ...
Lauren E. Maier +10 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Recent Development of Endo‐hepatology
DEN Open, Volume 7, Issue 1, April 2027.ABSTRACT Endo‐hepatology is a rapidly evolving field encompassing endoscopic diagnosis and treatment of hepatobiliary diseases, primarily using endoscopic ultrasound (EUS). Since its conceptualization in 2012, the field has expanded dramatically alongside advances in interventional EUS. A landmark 2024 review broadened the concept to include endoscopic
Akira Yamamiya +3 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 2151-2156, September 2026.ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio +11 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.Electroclinical findings supported diazepam‐responsive nonconvulsive status epilepticus (NCSE) in an older patient with drug‐resistant epilepsy and psychosis. After phenytoin treatment, continuous EEG helped monitor recurrence. Later symptoms were most consistent with interictal psychosis with a possible alternative psychosis component, emphasizing ...
Wataru Omori +4 more
wiley +1 more source