Results 81 to 90 of about 19,655 (167)
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
The Journal of Physiology, EarlyView.Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
The role of propranolol as a radiosensitizer in gastric cancer treatment
, 2018 Xinhua Liao, Prakash Chaudhary, Guanglin Qiu, Xiangming Che, Lin Fan General Surgery Department, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China Purpose: The National Comprehensive Cancer Network guidelines ...
Chaudhary P +4 more
core
Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.We address the long‐standing challenge of reactivity–selectivity trade‐off by precisely tuning the redox properties of Fe(IV), rather than simply accelerating its formation, to enable chemically efficient and low‐emission water treatment. ABSTRACT High‐valent iron oxo species (Fe(IV)) are attractive for wastewater treatment because of their high ...
Hongyu Zhou +9 more
wiley +2 more sources
eLife, 2019 Propranolol is an approved non-selective β-adrenergic blocker that is first line therapy for infantile hemangioma. Despite the clinical benefit of propranolol therapy in hemangioma, the mechanistic understanding of what drives this outcome is limited ...
Jeroen Overman +17 more
doaj +1 more source
Mechanisms reducing parasympathetic activity in chronic hypoxia
The Journal of Physiology, EarlyView.Abstract figure legend Parasympathetic activity is reduced in chronic hypoxia, but the underlying mechanism(s) are unclear. Using β‐adrenergic blockade to isolate parasympathetic control of heart rate at sea level and after 9‐12 days at high altitude, we investigated whether (i) chemoreflex activation, (ii) increased pulmonary ventilation and/or (iii ...
Lauren E. Maier +10 more
wiley +1 more source
The Development of a Novel Controlled Release Drug Delivery System [PDF]
, 2007 The aim of this research was to formulate, characterise and assess the feasibility of a novel drug delivery system known as the in situ gelling matrix (ISGM) where a hydrophilic polymer is suspended in a non-aqueous solvent that converts into a gel when ...
Babu, Kavitha Mary Vadakkel
core
The problem of propranolol poisoning [PDF]
Aims: Propranolol is licensed in the UK and elsewhere to relieve symptoms of anxiety. In overdose, propranolol poisoning can be serious, difficult to treat and potentially fatal.
Gray, Laurence +8 more
core +1 more source
Randomized, double-blind comparison of propranolol alone and a propranolol-verapamil combination in patients with severe angina of effort [PDF]
, 1983 This study compared propranolol alone with a combination of propranolol and verapamil in patients with severe, limiting angina of effort. Accordingly, 13 men (average age 57 years) with severe angina were enrolled in a study of 7 weeks' duration ...
Huxley, Robert L. +5 more
core +1 more source
Scientific Reports, 2018 Propranolol, a widely used non-selective beta-adrenergic receptor blocker, was recently shown to display anticancer properties. Its potential to synergize with certain drugs has been also outlined.
Laura Brohée +6 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source