Results 101 to 110 of about 41,520 (219)

Conduction System Pacing‐Induced Ventricular Arrhythmia: Case Report

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.
In structurally compromised ventricles, LBBAP may unmask conduction–repolarization heterogeneities, increasing susceptibility to malignant ventricular arrhythmias in the early post‐implant period. Careful monitoring and individualized risk assessment are crucial in high‐risk patients.
Serhat Kesriklioglu   +5 more
wiley   +1 more source

A role for epithelium‐derived 6‐nitrodopamine on human ureter contractility

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2360-2375, May 2026.
Abstract Background and Purpose To investigate the basal release of 6‐nitrodopamine (6‐ND) from human isolated ureter and the role of this novel catecholamine in the ureter contractility. Experimental Approach Ureters from 67 brain‐dead organ donors (40 males and 27 females) were used during kidney transplantation procedures.
Wilmar Azal Neto   +12 more
wiley   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1727-1746, May 2026.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun   +2 more
wiley   +1 more source

A Scoping Review of Non‐Opioid Therapeutics for Opioid Withdrawal: Translational Relevance to Neonatal Opioid Withdrawal Syndrome (NOWS) Research

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT In the wake of the ongoing opioid epidemic, the incidence of neonatal opioid withdrawal syndrome (NOWS) has surged. While the short‐term effects of NOWS are well‐characterized, long‐term physiological and molecular consequences remain unclear.
Sara L. Mills‐Huffnagle   +4 more
wiley   +1 more source

Post‐marketing safety of CGRP monoclonal antibodies and gepants: A systematic review of spontaneous reporting system data

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1128-1147, May 2026.
Abstract Objective Calcitonin gene‐related peptide (CGRP) inhibitors, including monoclonal antibodies (mAbs) and small‐molecule antagonists (gepants), have transformed migraine treatment. Although clinical trials established their efficacy and initial safety, post‐marketing surveillance is essential for understanding their real‐world safety profile in ...
Martina Giacon, Salvatore Terrazzino
wiley   +1 more source

Combination Therapy With AOPT Intense Pulsed Light (Dual‐Band Vascular Filter) and 1064 nm Nd:YAG Laser for Solitary, Superficial Infantile Hemangioma: A Retrospective Study

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Objective This study evaluated the efficacy and safety of a sequential protocol for treating solitary, superficial infantile hemangioma (IH). The protocol combined an Advanced Optimal Pulse Technology (AOPT) intense pulsed light system, which was equipped with a novel dual‐band vascular filter, with a subsequent long‐pulsed 1064 nm Nd:YAG ...
Zhang Jiang   +8 more
wiley   +1 more source

Comparative Pharmacokinetics of Intranasal or Intramuscular Atipamezole in Unsedated Dogs and Efficacy for Reversal of Xylazine Sedation

open access: yesJournal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 3, Page 257-266, May 2026.
ABSTRACT The objectives of this study were to evaluate ATIP pharmacokinetics (PK) in healthy Beagle dogs after IM and IN dosing (Phase I), and to compare the rate of reversal of IM versus IN routes for xylazine (XYL) sedation (Phase II). This study was comprised of two sequential, randomized, crossover experiments. The initial PK study dosed ATIP by IN
Vanessa E. Cowan   +7 more
wiley   +1 more source

Steady‐state Purkinje cell activity has limited predictive power for cerebellar output in disease

open access: yesThe Journal of Physiology, Volume 604, Issue 10, Page 3964-3983, 15 May 2026.
Abstract figure legend Cerebellar dysfunction can give rise to various movement disorders. Misfiring cerebellar neurons often underlie this dysfunction. Because Purkinje cells form inhibitory synapses onto cerebellar nuclei cells, it has been presumed that spike activity changes in Purkinje cells cause inverse spike activity changes in the downstream ...
Alyssa M Lyon   +2 more
wiley   +1 more source

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