Results 101 to 110 of about 42,221 (227)

Successful propranolol therapy for infantile hepatic hemangioma with cardiac failure

JPGN Reports, Volume 7, Issue 3, Page 387-390, August 2026.
Abstract Infantile hepatic hemangioma (IHH) can cause severe complications such as high‐output cardiac failure and growth faltering, requiring prompt diagnosis and intervention. In the absence of standardized treatment guidelines, propranolol has emerged as an effective and well‐tolerated therapy.
Fadhel Al Ateeqi, Ala K. Shaikhkhalil, Haitham Talo, Naeem Jagirdar, Mahdia AL‐Haidar   +4 more
wiley   +1 more source

Propranolol for infantile hemangiomas: a preliminary report on efficacy and safety in very low birth weight infants

The Turkish Journal of Pediatrics, 2010
Despite the relatively recent introduction of propranolol in the treatment of infantile hemangiomas, there can be little doubt of its efficacy. With regard to safety issues, there are no prior data for very low weight infants.
Ayşe Erbay, Faik Sarialioglu, Bariş Malbora, Selman Vefa Yildirim, Birgül Varan, Aylin Tarcan, Hande Gülcan, Senay Demir, Murat Derbent, Nihal Uslu, Aslihan Abbasoğlu   +10 more
doaj  

Subthalamic Nucleus Deep Brain Stimulation Improves Kinetic Tremor in Parkinson's Disease

Movement Disorders Clinical Practice, Volume 13, Issue 8, Page 1926-1932, August 2026.
Abstract Background Although resting tremor is a characteristic feature of Parkinson's disease (PD), many patients also suffer from action tremor. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in reducing motor symptoms. However, it is unclear to what extent STN‐DBS improves action tremor in PD, particularly kinetic tremor.
Iwan Grooters, Bart E.K.S. Swinnen, Yarit Wiggerts, Maarten Bot, Pepijn van den Munckhof, P. Rick Schuurman, Martijn Beudel, Rob M.A. de Bie, Arthur W.G. Buijink   +8 more
wiley   +1 more source

Uptake and Transport of Monotropein and Monotropein Esters in a Caco‐2/HT29‐MTX‐E12 Co‐Culture Model

Molecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
Monotropein and its naturally occurring ester derivatives (monotropein‐10‐coumarate and monotropein‐10‐cinnamate) from Gaultheria spp. berries exhibit limited intestinal permeability in a validated Caco‐2:HT29‐MTX‐E12 co‐culture model. Absorption occurs predominantly via passive diffusion, with partial SGLT1‐ and OATP‐mediated uptake contribution for ...
Christian Zielinski, Victor Schmalle, Luise A. Lauer, Tim Hammerschick, Felix Rüttler, Walter Vetter, Jan Frank, Felipe Jiménez‐Aspee   +7 more
wiley   +1 more source

Ultrasmall Cyclodextrin‐Based Nanogels as Drug Delivery Systems

ChemistryOpen, Volume 15, Issue 8, August 2026.
Cyclodextrin (CD) nanogels provide a highly effective, biocompatible platform for advanced drug delivery. These specialized networks successfully encapsulate active ingredients, significantly improving overall drug solubility. Furthermore, the resulting nanogels exhibit enhanced toxicity toward cancer cell lines compared to the parent CDs.
Andrea Cesari, Simona Braccini, Maria Antonietta Casulli, Kento Ishigaki, Takeshi Hashimoto, Takashi Hayashita, Dario Puppi, Fabio Bellina   +7 more
wiley   +1 more source

A Physiologically Based Pharmacokinetic Model to Predict Potential Drug–Drug Interactions of TPN171, a Novel Phosphodiesterase Type 5 Inhibitor

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
ABSTRACT TPN171 is a potent phosphodiesterase type 5 inhibitor used to treat pulmonary arterial hypertension and erectile dysfunction, primarily metabolized by CYP3A4. This study aimed to evaluate its drug–drug interaction (DDI) potential and determine the optimal dosing when co‐administered with CYP3A4 modulators.
Guanghui Tian, Tao Chen, Lei Li, Zhiqiang Wang, Hao Yang, Jiaxiang Juan, Yuanqin Duan, Jianghong Pei, Jingying Jia   +8 more
wiley   +1 more source

Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling. ABSTRACT pH‐dependent drug–drug interactions (DDIs) commonly occur when acid‐reducing agents (ARAs) are co‐administered with weakly basic drugs.
Yuanfang Qin, Lehua Yu, Tao Chen, Yonghui Zuo, Hongyun Wang, Guoping Yang, Qi Pei   +6 more
wiley   +1 more source

Clinical Remission of an Unresectable Presumptive Haemangiosarcoma in a Dog Treated With Toceranib, Piroxicam, and Propranolol: A Case Report. [PDF]

Vet Med Sci
Park WD.
europepmc   +1 more source

Bayesian Estimation of the Binomial Parameter in Adaptive Designs With Treatment Selection

Statistics in Medicine, Volume 45, Issue 18-19, August 2026.
ABSTRACT It is well‐known that results from adaptive multi‐arm experiments with treatment selection are subject to the bias of the selection process. In this article, we consider designs with a binary outcome that begin with randomized parallel arms.
Pierre Bunouf, Jean‐Marie Boher
wiley   +1 more source

Key cellular subpopulations and mechanisms of propranolol in infantile hemangioma: insights from single-cell omics. [PDF]

Front Med (Lausanne)
Chen M, Liu J, Meng J, Chen Q.
europepmc   +1 more source