Results 161 to 170 of about 106,571 (324)

Understanding CPVT pathogenic mechanisms based on mutation location within RyR2: towards personalized medicine?

open access: yes
The Journal of Physiology, EarlyView.
Jean‐Pierre Benitah   +2 more
wiley   +1 more source

Beyond the Michaelis–Menten: Evaluation of a tQSSA‐Based IVIVE Approach for Predicting In Vivo Intrinsic Clearance From Hepatocyte Assays

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT The classical Michaelis–Menten model, under the standard quasi‐steady‐state approximation (sQSSA), is widely used in in vitro‐in vivo extrapolation (IVIVE) studies using hepatocyte or human liver microsomal (HLM) assays to predict intrinsic hepatic clearance (Clint,vitro$$ {\mathrm{Cl}}_{\operatorname{int},\mathrm{vitro}} $$).
Ngoc‐Anh Thi Vu   +6 more
wiley   +1 more source

Re: Propranolol for infantile haemangiomas: Early experience from a tertiary center

open access: diamond, 2014
Anand Pandey   +3 more
openalex   +1 more source

Higher Doses of Oral Propranolol for Resistant Infantile Haemangio-mas. [PDF]

open access: yesActa Derm Venereol
Dreyfus I   +11 more
europepmc   +1 more source

Pharmacological and neurophysiological aspects of space/motion sickness [PDF]

open access: yes
A motorized motion testing device modeled after a Ferris wheel was constructed to perform motion sickness tests on cats. Details of the testing are presented, and some of the topics covered include the following: xylazine-induced emesis; analysis of the ...
Crampton, George H., Lucot, James B.
core   +1 more source

Extrasystoles on 24‐h Holter Monitoring During the First Year of Life

open access: yesActa Paediatrica, Volume 115, Issue 2, Page 370-377, February 2026.
ABSTRACT Aim To assess the natural course of extrasystoles and their association with tachyarrhythmias on 24‐h Holter monitoring during the first year of life. Methods A retrospective chart review was performed among newborns referred for 24‐h Holter monitoring at Tampere University Hospital from 2011 to 2017.
Asta Uusitalo   +5 more
wiley   +1 more source

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