Results 11 to 20 of about 96,658 (272)
Pharmaceutics, 2021 Oral propranolol hydrochloride has been the first-line treatment for infantile hemangioma (IH), whereas systemic exposure to propranolol has the potential of causing serious adverse reactions.
Jingjing He +6 more
doaj +2 more sources
Propranolol: A 50-year historical perspective
Annals of Indian Academy of Neurology, 2019 Propranolol is a beta-adrenergic receptor antagonist that was developed by the British scientist Sir James Black primarily for the treatment of angina pectoris, more than 50 years ago.
A V Srinivasan
doaj +2 more sources
Propranolol 0.2% Eye Micro-Drops for Retinopathy of Prematurity: A Prospective Phase IIB Study
Frontiers in Pediatrics, 2019 Background: Oral propranolol reduces retinopathy of prematurity (ROP) progression, although not safely. Propranolol 0.1% eye micro-drops administered to newborns with stage 2 ROP are well-tolerated, but not sufficiently effective.Methods: A multi-center ...
Luca Filippi +41 more
doaj +2 more sources
Scientific Reports, 2018 Propranolol, a widely used non-selective beta-adrenergic receptor blocker, was recently shown to display anticancer properties. Its potential to synergize with certain drugs has been also outlined.
Laura Brohée +6 more
doaj +2 more sources
JAMA Otolaryngology - Head and Neck Surgery, 2021 Importance Propranolol has become the first-line therapy for problematic infantile hemangiomas (IHs) that require systemic therapy. However, different adverse events have been reported during propranolol treatment.
Yi Ji +13 more
semanticscholar +1 more source
Frontiers in Pediatrics, 2022 Background and PurposeThis study was conducted to explore the plasma drug concentration of propranolol in Chinese Han patients with infantile haemangioma (IH) and the influencing factors, as well as the relationship among plasma drug concentrations of ...
Li Li +11 more
doaj +1 more source
Noninferiority and Safety of Nadolol vs Propranolol in Infants With Infantile Hemangioma
JAMA pediatrics, 2021 Key Points Question Is nadolol noninferior to propranolol in the management of infantile hemangioma? Findings In this randomized clinical trial, infantile hemangiomas treated with nadolol showed a larger change in size and color compared with propranolol,
E. Pope +6 more
semanticscholar +1 more source
Propranolol Ameliorates the Antifungal Activity of Azoles in Invasive Candidiasis
Pharmaceutics, 2023 The effectiveness of current antifungal therapies is hampered by the emergence of drug resistance strains, highlighting an urgent need for new alternatives such as adjuvant antifungal treatments.
Venkatesh Mayandi +9 more
doaj +1 more source
Clinical Cancer Research, 2020 Purpose: Increased β-adrenergic receptor (β-AR) signaling has been shown to promote the creation of an immunosuppressive tumor microenvironment (TME). Preclinical studies have shown that abrogation of this signaling pathway, particularly β2-AR, provides ...
S. Gandhi +18 more
semanticscholar +1 more source
Propranolol Modulates Cerebellar Circuit Activity and Reduces Tremor
Cells, 2022 Tremor is the most common movement disorder. Several drugs reduce tremor severity, but no cures are available. Propranolol, a β-adrenergic receptor blocker, is the leading treatment for tremor. However, the in vivo circuit mechanisms by which propranolol
Joy Zhou +9 more
doaj +1 more source