Results 111 to 120 of about 8,088 (248)
BRICHOS interactions with amyloid proteins and implications for Alzheimer disease [PDF]
To date, about 30 diseases, in which amyloid fibrils form extracellular deposits, have been identified in humans. It is not known if the fibrils have a function, like storage of misfolded proteins, or if they just reflect failure of the cell to manage ...
Dolfe, Lisa
core +1 more source
ABSTRACT Persistent chylomicronemia is associated with severe hypertriglyceridemia (sHTG) and plasma triglycerides (TG) levels sustainably > 10 mmol/L (880 mg/dL) despite lipid lowering therapies. The main risk of persistent chylomicronemia is acute pancreatitis (AP). During the second and third trimester of pregnancy, TG levels significantly increase,
Miriam Larouche +6 more
wiley +1 more source
Employs a literature review to describe intrinsic motivation as the force behind pro-social behavior, or when individuals willingly engage in behavior that is costly to them but benefits others.
Brock, J. Michelle +2 more
core +1 more source
The Role of Proprotein Convertases in Upper Airway Remodeling. [PDF]
Lee SN, Yoon JH.
europepmc +1 more source
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in the treatment of dyslipidemia
А. А. Shikaleva +2 more
openalex +2 more sources
This article supports that ANGPTL4 secreted factor is induced transcriptionally and activated by proteolytic cleavage during senescence, contributing to the production of a pro‐inflammatory SASP. In the senescent cell microenvironment, ANGPTL4 could thus contribute to senescence‐dependent alterations such as inflammation and tumor initiation.
Gabriela Makulyte +20 more
wiley +1 more source
Addressing unmet needs for chronic kidney disease treatment in type 1 diabetes: A review
Abstract Chronic kidney disease (CKD) is a serious complication occurring in nearly one of three people with type 1 diabetes (T1D). Major therapeutic advances have been made in the management of CKD for people with type 2 diabetes (T2D), thereby improving their kidney, cardiovascular, and survival outcomes.
Katherine R. Tuttle +3 more
wiley +1 more source
PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease. [PDF]
BACKGROUND: Despite the availability of effective drug therapies that reduce low-density lipoprotein (LDL)-cholesterol (LDL-C), cardiovascular disease (CVD) remains an important cause of mortality and morbidity.
Casas, Juan P +5 more
core +2 more sources

