The Yeast Proprotein Convertase Encoded by YAP3 Is a Glycophosphatidylinositol-anchored Protein That Localizes to the Plasma Membrane [PDF]
, 1995 Josée Ash +4 more
openalex +1 more source
Proteina konbertasen adierazpena minbizi-zelula parental eta minbizi-zelula ametan (CSC) [PDF]
, 2017 [EUS] Minbizia hilkortasun oso handiko gaitza da, 2015. urtean 8,8 milioi hildako eragin zituen. Nahiz eta tratamendu bortitz eta luzeak aplikatu, askotan denbora baten ostean gaixotasunaren errekurrentzia gertatzen da, baita metastasiak ere.
Oiartzabal Narbarte, Irati
core
Processing of Human Intestinal Prolactase to an Intermediate Form by Furin or by a Furin-like Proprotein Convertase [PDF]
, 1998 José Emilio Mesonero +2 more
openalex +1 more source
Obesity Reviews, EarlyView.Summary With the evolving landscape of diseases, heart failure with preserved ejection fraction (HFpEF) now encompasses more than half of all heart failure patients. This condition is clinically diverse, involving multiple organ systems and often occurring alongside the aging process.
Zhongwen Qi +6 more
wiley +1 more source
Hyperphagia in Bardet–Biedl syndrome: Pathophysiology, burden, and management
Obesity Reviews, EarlyView.Summary Bardet–Biedl syndrome (BBS) is a rare, genetically heterogeneous, and highly pleiotropic autosomal recessive ciliopathy. Patients typically present with early loss of vision, hyperphagia, severe obesity, learning difficulties, and renal dysfunction. In patients with BBS, dysfunction of the immotile primary cilia in the hypothalamic melanocortin‐
Philip L. Beales +7 more
wiley +1 more source
Dynamic palmitoylation of lymphoma proprotein convertase prolongs its half-life, but is not essential for trans-Golgi network localization [PDF]
, 2000 Jan-Willem H. P. VAN DE LOO +5 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend We investigated electrophysiological changes in lateral habenula (LHb) neurons induced by chronic social defeat stress in mice. LHb neurons exhibited short (<400 ms) rebound depolarizing potentials (short‐RDPs) or long‐RDPs (order of seconds) (long‐RDPs) after the offset of hyperpolarization. The incidence of long‐RDP neurons was
Kenji Yamaoka +12 more
wiley +1 more source
Endoproteolytic processing of integrin pro-α subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7 [PDF]
, 2000 Jean‐Claude Lissitzky +7 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A, Sarcopenic obesity is defined as the age‐related loss of skeletal muscle mass and function that often leads to the progression of comorbidities, such as Alzheimer's disease (AD). Though the exact link between the two diseases is unknown, alterations in brain‐derived neurotrophic factor (BDNF) may be a contributor.
Emily N. Copeland +4 more
wiley +1 more source
The discovery of PCSK9 inhibitors: A tale of creativity and multifaceted translational research. [PDF]
, 2013 Elguindy, A, Yacoub, MH
core +1 more source