Results 161 to 170 of about 18,795 (277)
Novel insights into the function and regulation of group X secretory phospholipase A\u3csub\u3e2\u3c/sub\u3e [PDF]
, 2013 Group X secretory phospholipase A2 (GX sPLA2) hydrolyzes membrane phospholipids producing free fatty acids and lysophospholipids. Previous studies from our lab suggest that mice with targeted deletion of GX sPLA2 (GX KO) have increased age-related weight
Layne, Joseph D, Jr
core +1 more source
Processing of β-Secretase by Furin and Other Members of the Proprotein Convertase Family [PDF]
, 2001 John W.M. Creemers +8 more
openalex +1 more source
Liver International Communications, Volume 6, Issue 2, June 2025.ABSTRACT Loss of effective arterial blood volume, secondary hyperaldosteronism, adrenergic activation and nonosmotic hypersecretion of vasopressin induce sodium and water retention in cirrhotic patients with ascites. The mechanisms of sodium retention that precede ascites formation remain elusive.
Giovanni Sansoè +2 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.ABSTRACT The invention of a therapeutic begins by characterizing features that differentiate healthy versus diseased states; this often presents as changes in the concentration of an analyte. Examples include elevated blood glucose in diabetes, high cholesterol in heart disease, and protein aggregation in neurodegeneration.
Rebecca A. Kohnz +10 more
wiley +1 more source
Inhibitory Specificity and Potency of proSAAS-derived Peptides toward Proprotein Convertase 1 [PDF]
, 2001 Ajoy Basak +6 more
openalex +1 more source
Substrate selectivity by proprotein convertases
Developmental Biology, 2007 Sylvia Nelsen, Jan L. Christian
openaire +2 more sources
Landscape of rare‐allele variants in cultivated and wild soybean genomes
The Plant Genome, Volume 18, Issue 2, June 2025.Abstract Rare‐allele variants are important for crop improvement because they can be linked to important traits. However, genome‐wide distribution and annotation of rare‐allele variants have not been reported. We analyzed sequencing data from 1556 soybean accessions and found 6,533,419 rare‐allele variants in Glycine max and 941,274 in Glycine soja ...
Zhi Liu +9 more
wiley +1 more source
Effects of Age and Retinal Degeneration on the Expression of Subtilisin-like Proprotein Convertases in the Visual Cortex of Mice [PDF]
, 2009 Postnatal development of the visual cortex is a complex process that involves a number of molecules like growth factors, neuropeptides and cholesterol. Neurotrophins, like NGF, BDNF, NT-3, and NT-4, which are synthesized as precursors, also play a very ...
Chinnaswamy, Krishnapriya
core
Single-nucleotide polymorphisms of the proprotein convertase subtilisin/kexin type 5 (PCSK5) gene [PDF]
, 2001 Hujun Cao +3 more
openalex +1 more source
Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3477-3489, June 2025.Abstract Aims [D3,G40,K41.C16 diacid]exendin‐4 (acyl‐ExD3) and [F1,G40,K41.C16 diacid]exendin‐4 (acyl‐ExF1) are oppositely biased glucagon‐like peptide‐1 (GLP‐1) receptor agonists that preferentially promote β‐arrestin recruitment or G protein‐induced signalling, respectively.
Melanie Modder +9 more
wiley +1 more source