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The Proprotein Convertases, 20 Years Later
2011The proprotein convertases (PCs) are secretory mammalian serine proteinases related to bacterial subtilisin-like enzymes. The family of PCs comprises nine members, PC1/3, PC2, furin, PC4, PC5/6, PACE4, PC7, SKI-1/S1P, and PCSK9 (Fig. 3.1). While the first seven PCs cleave after single or paired basic residues, the last two cleave at non-basic residues ...
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Proprotein Convertase 1/3 Deficiency
The Indian Journal of Pediatrics, 2017Gurinder Kumar +2 more
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