Results 61 to 70 of about 8,955 (198)

Antineutrophil Cytoplasmic Antibody-Positive Cutaneous Leukocytoclastic Vasculitis Associated with Propylthiouracil Therapy

, 2008
Background: Vasculitis is a rare complication of therapy with propylthiouracil (PTU). Although PTU-induced antineutrophil cytoplasmic antibody (ANCA) positivity is not uncommon, ANCA positive vasculitis associated with PTU therapy presenting as lesions ...
沈宜萱;朱家瑜;余幸司, SHEEN, YI-SHUAN;CHU, CHIA-YU;YU, HSIN- SU   +1 more
core  

Selective Liquid-Chromatographic Assay for Propylthiouracil in Plasma

, 1991
A liquid chromatographic assay was developed to quantitate propylthiouracil in plasma using an internal standard, 5-propyl-2-thiouracil, of similar structure and physical properties.
Yap, AS, Williams, JP, R.H. Mortimer, A.S. Yap, G.R. Cannell, Cannell, GR, J.P. Williams, Mortimer, RH   +7 more
core   +1 more source

Withania somnifera Root Extract Ameliorates PTU‐Induced Hypothyroidism by Regulating Hormone Levels and Gene Expression in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Graphical abstract for the integrated in silico and in vivo approach demonstrating the Methanolic extract of Withania somnifera root ameliorated PTU‐induced hypothyroidism through the regulation of thyroid hormone levels, gene expression, and thyroid histopathology.
Md. Saud Hossain, Md. Shah Poran Shuvo, M. Maruf Hasan Talukder, Shahidullah, Sumaia Jannat, S. M. Riaduzzaman Niaz, Md Sohel, Md. Khairul Islam   +7 more
wiley   +1 more source

Occult Pulmonary Hemorrhage as a Rare Presentation of Propylthiouracil-Induced Vasculitis

, 2011
Propylthiouracil, a drug commonly used to treat hyperthyroidism, is known to cause antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis as a rare complication. The wide clinical spectrum of propylthiouracil-induced vasculitis ranges from mild
Yi-Chan Tsai, Tsung-Chieh Yao, Yu-Ling Tu, Jing-Long Huang   +3 more
core   +1 more source

Graves' Disease: Prospective Up to 10‐Year Outcome for 100 Consecutive Individuals at a Single Centre

Clinical Endocrinology, Volume 105, Issue 1, Page 122-125, July 2026.
Muhammad Muneeb Ibad, Mrinalini Srichandran, Sangeeth Veluchamy, Waseem Majeed, Natalie Gallant, Sarah Jamil, Rupinder Kochhar, Suhani Bahl, Lakdasa Premawardhana, Peter Taylor, Onyebuchi Okosieme, Colin Dayan, Adrian Heald   +12 more
wiley   +1 more source

Kisspeptin Restores Placental mTOR Signaling and Improves Glucose Homeostasis Mediators Disrupted by Maternal Hypothyroidism in Rats

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Reduced placental mTOR signaling is associated with intrauterine growth restriction and impaired maternal and placental metabolism. Since maternal hypothyroidism induces intrauterine growth restriction, and maternal treatment with kisspeptin‐10 (Kp10) has been shown to improve feto‐placental development in hypothyroid rats, this study ...
Bianca Reis Santos, Jeane Martinha dos Anjos Cordeiro, Luciano Cardoso Santos, Cleisla Souza Oliveira, Maria Clara Pascoal Santos Alvarez, Natália Panhoca Rodrigues, Jorge Lopez‐Tello, Amanda N. Sferruzzi‐Perri, Rogéria Serakides, Juneo Freitas Silva   +9 more
wiley   +1 more source

Risk factors for obesity development in Caucasian and Zulu women : personal and parental weight history, weight management practices, eating behaviour and taste sensitivity : a case-control study

, 2011
Obesity is a significant health problem in South Africa and the need for intervention in this regard has been emphasized. Existing information indicates that modifiable risk factors such as diet and physical activity may be contributing to this problem ...
Herrmann, Fiona
core  

Propylthiouracil induced leukocytoclastic vasculitis: A rare manifestation

, 2013
Propylthiouracil (PTU) is a common drug used in patients with hyperthyroidism. It may cause perinuclearantineutrophil cytoplasmic antibodies (p-ANCA) in few patients with Graves′ disease.
Mustafa Volkan Demir, Selçuk Yaylaci, Semra Ayturk, Ali Tamer   +3 more
core   +1 more source

Study of Salvia Officinalis Hydroethanolic Extract on Serum Thyroid Hormone Levels in Hypothyroid Male Rat

پزشکی بالینی ابن سینا, 2013
Introduction & Objective: Medicinal plants are widely used throughout the world. Hypothyroid-ism is an important hormonal disease that causes some disorders in body organs. Salvia officinalis has been known as a medicinal plant since ancient times.
Naser Mirazi, Nasrin Abdolmaleki, Minoo Mahmoodi   +2 more
doaj  

Signal Amplification in the HPT Axis—Evidence for Its Existence, Location, Significance, and Molecular Mechanisms

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Thyroid hormones (THs) are under negative feedback regulation via the hypothalamic–pituitary‐thyroid (HPT) axis. How this axis operates to keep the circulating THs within a narrow physiological range is not well understood quantitatively. Led by the design principle of robust homeostatic feedback control, here we review and synthesize the ...
Li Jing, Sarahna A. Moyd, Qiang Zhang
wiley   +1 more source