Results 41 to 50 of about 8,955 (198)

HEMATOLOGICAL DISORDERS OF PROPYLTHIOURACIL IN THYROID PATIENTS AT TERTIARY CARE HOSPITAL OF HYDERABAD

Pakistan Armed Forces Medical Journal, 2021
Objective: To find out the frequency of anemia, agranulocytosis and thrombocytopenia in hyperthyroid patients after the use of propylthiouracil. Study Design: Cross sectional study.
Uzma Naz Shaikh, Muhammad Ali Ghoto, Abdullah Dayo, Mudassar Iqbal Arain, Jibran Khan   +4 more
doaj  

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

CD1a expression in psoriatic skin following treatment with propylthiouracil, an antithyroid thioureylene [PDF]

, 2003
BackgroundThe antithyroid thioureylenes, propylthiouracil (PTU) and methimazole (MMI), are effective in the treatment of patients with plaque psoriasis. The mechanism of action of the drugs in psoriasis is unknown.
Ronald J Barr, Nanda, Vandana S, Barr, Ronald J, Elias, Alan N, Alan N Elias, Vandana S Nanda   +5 more
core   +1 more source

Curcumin exerts protective effects on the thyroid gland in propylthiouracil-treated rats

Folia Histochemica et Cytobiologica, 2023
INTRODUCTION: Among the plant ingredients, some compounds interfere with the functions of the thyroid gland. However, there is limited research on the effect of curcumin (CMN) on the functions of this gland.
Monika A. Papież
doaj   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Vasculitis and antineutrophil cytoplasmic autoantibodies associated with propylthiouracil therapy

, 1993
Vasculitis is a rare complication of propylthiouracil therapy. Antineutrophil cytoplasmic antibodies (ANCA) have been described in association with several vasculitic disorders. We report detection of ANCA against human neutrophil elastase, proteinase 3,
Gans, R O; id_orcid, von dem Borne, A E, Nikkels, R. E., Gans, R. O., Dolman, K M, Donker, A. J., Vervaat, T J, Goldschmeding, R, Vervaat, T. J., Maingay, D., Zevenbergen, G., Zevenbergen, G, Donker, A J, von dem Borne, A. E., Maingay, D, Dolman, K. M., Nikkels, R E, Goldschmeding, R., Gans, R O   +18 more
core   +1 more source

Propylthiouracil-induced necrotizing vasculitis

Turkish Journal of Plastic Surgery
Propylthiouracil (PTU)-induced vasculitis is a rare antineutrophilic cytoplasmic antibody-associated vasculitis involving small vessels. The patients are often present with constitutional symptoms such as skin rash, fever, sore throat, and joint pain ...
Nuh Evin, Fatih Osman Demir
doaj   +1 more source

6-n-propylthiouracil taste disruption and TAS2R38 nontasting form in Parkinson's disease

, 2018
Background: The few studies that evaluated taste function in Parkinson's disease (PD) showed inconsistent results. The inherited ability to taste the bitter compound of 6-n-propylthiouracil has been considered to be a paradigm of general taste perception.
Melis, Melania, Morelli, Micaela, Cossu, Giovanni, Melis, Maurizio, Melis, Marta, Tomassini Barbarossa, Iole, Sarchioto, Marianna   +6 more
core   +1 more source

Colorimetric Determination of Thioamide Drugs Based on the Surface Plasmon Resonance Band of Colloidal Silver Nanoparticles [PDF]

شیمی کاربردی روز, 2013
In this article, we report a new method for the determination of two thioamide drugs, propylthiouracil (PTU) and methimazole (MMZ), with unmodified silver nanoparticles (AgNPs).
Jafar Abolhasani, Azam Samadi, Ebrahim Ghorbani-Kalhor, Nima Serrpoush Hamid   +3 more
doaj   +1 more source

Case Report of Combined Central and Peripheral Demyelination: Treated With Ofatumumab

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background and Objectives Combined central and peripheral demyelination (CCPD) is a rare autoimmune‐mediated disorder characterized by demyelination affecting both the central nervous system and peripheral nervous system. The involvement of the CNS typically manifests as longitudinally extensive transverse myelitis and optic neuritis, whereas ...
Lili Liu, Zhigang Zhong, Haijun Wu, Jun Hu, Juanjuan Chen   +4 more
wiley   +1 more source