Teratogenic effects of Propylthiouracil on Swiss albino mice fetuses – A gross study
Background: Propylthiouracil is an antithyroid drug used to treat hyperthyroidism in pregnancy, as euthyroid state is necessary for optimal pregnancy outcome.
Samta Tiwari +2 more
doaj +1 more source
Development of a molecular method for the rapid screening and identification of the three functionally relevant polymorphisms in the human TAS2R38 receptor gene in studies of sensitivity to the bitter taste of PROP [PDF]
The objective of this work was to develop a rapid screening method to identify the three single nucleotide polymorphisms (SNPs) in the TAS2R38 gene, with the aim of providing a significant contribution to studies designed to assess sensitivity to the ...
Atzori, E, Orrù, R, Padiglia, A
core +2 more sources
Congenital Bands with Intestinal Malrotation after Propylthiouracil Exposure in Early Pregnancy
Exposure to propylthiouracil in early pregnancy may be associated with an increased risk of birth defects. But the spectrum of associated congenital anomalies is not yet well defined.
Alexander A. Leung +4 more
doaj +1 more source
Background: Propylthiouracil (PROP) (a medicated tool) and hormonal fingerprint (second to fourth digits [2D:4D]) ratio can be used for detection of caries which is most prevalent oral health disease. Aim: This study aims to determine the role of genetic
Simran Hareshkumar Dusseja +3 more
doaj +1 more source
EFFECT OF PROPYLTHIOURACIL-INDUCED HYPOTHYROIDISM ON REPRODUCTIVE EFFECIENCY OF ADULT MALE RATS [PDF]
This study is designed to evaluate the effect of hypothyroidism on reproductive efficiency of adult male rats. Hypothyroid state was induced by administration of anti-thyroid drug propylthiouracil (PTU) (15 mg/kg b.w) orally by gavage for 45 days. Twenty
Jassim.M.A.Alkalby Sarah.J.S.Alzerjawi
doaj +1 more source
The thyroid hormones (THs) regulate various physiological mechanisms in mammals, such as cellular metabolism, cell structure, and membrane transport.
Zhipeng Wang +10 more
doaj +1 more source
Pathologic manifestations of levamisole-adulterated cocaine exposure. [PDF]
UnlabelledRheumatic manifestations of cocaine have been well described, but more recently, a dramatic increase in the levamisole-adulterated cocaine supply in the United States has disclosed unique pathologic consequences that are distinct from pure ...
Jen, Kuang-Yu, Nolan, Amber L
core +1 more source
This study was undertaken to investigate the protective role of Ginger against the hypothyroidism induce by Propylthiouracil in male rats on serum lipids.
Nabeel M. N. Al-Sharafi +1 more
doaj +1 more source
Variation in TAS2R receptor genes explains differential bitterness of two common antibiotics
For pharmaceuticals to deliver their full benefits with maximum efficacy, patients need to follow recommended dosing schedules, in terms of amount and frequency.
Alissa A. Nolden +2 more
doaj +1 more source
CD1a expression in psoriatic skin following treatment with propylthiouracil, an antithyroid thioureylene [PDF]
BackgroundThe antithyroid thioureylenes, propylthiouracil (PTU) and methimazole (MMI), are effective in the treatment of patients with plaque psoriasis. The mechanism of action of the drugs in psoriasis is unknown.
Alan N Elias +42 more
core +1 more source

