Cytotoxic 4-Hydroxyprorocentrolide and Prorocentrolide C from Cultured Dinoflagellate Prorocentrum lima Induce Human Cancer Cell Death through Apoptosis and Cell Cycle Arrest [PDF]
Prorocentrolide and its analogs, the novel naturally derived antitumor agents, have recently been identified in the dinoflagellate Prorocentrum lima.
Seon Min Lee +3 more
doaj +2 more sources
Discovering a New Okadaic Acid Derivative, a Potent HIV Latency Reversing Agent from Prorocentrum lima PL11: Isolation, Structural Modification, and Mechanistic Study [PDF]
Marine toxins (MTs) are a group of structurally complex natural products with unique toxicological and pharmacological activities. In the present study, two common shellfish toxins, okadaic acid (OA) (1) and OA methyl ester (2), were isolated from the ...
Dong Huang +9 more
doaj +2 more sources
Profiling of Extracellular Toxins Associated with Diarrhetic Shellfish Poison in Prorocentrum lima Culture Medium by High-Performance Liquid Chromatography Coupled with Mass Spectrometry [PDF]
Extracellular toxins released by marine toxigenic algae into the marine environment have attracted increasing attention in recent years. In this study, profiling, characterization and quantification of extracellular toxin compounds associated with ...
Lei Pan +7 more
doaj +2 more sources
Improved Isolation Procedures for Okadaic Acid Group Toxins from Shellfish (Mytilus edulis) and Microalgae (Prorocentrum lima) [PDF]
Okadaic acid (OA) group toxins may accumulate in shellfish and can result in diarrhetic shellfish poisoning when consumed by humans, and are therefore regulated.
Jane Kilcoyne +6 more
doaj +2 more sources
Nowadays, diarrheic shellfish toxicity (DSP) toxin and microplastics (MPs) are commonly found in coastal waters worldwide. Due to their widespread use, their persistence and toxicity, they may induce adverse effects on Mytilus coruscus.
Chen-Ying Xie +2 more
exaly +3 more sources
Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis [PDF]
Okadaic acid (OA) and dinophysistoxins (DTXs) are the main toxins responsible for diarrhetic shellfish poisoning (DSP) intoxications during harmful algal blooms (HABs).
María Verónica Prego-Faraldo +4 more
doaj +2 more sources
Molecular Phylogeny, Morphology, Growth and Toxicity of Three Benthic Dinoflagellates Ostreopsis sp. 9, Prorocentrum lima and Coolia monotis Developing in Strait of Gibraltar, Southwestern Mediterranean [PDF]
Few works have been carried out on benthic harmful algal blooms (BHAB) species in the southern Mediterranean and no data are available for the highly dynamic Strait of Gibraltar (western Mediterranean waters). For the first time, Ostreopsis sp.
Mustapha Ibghi +11 more
doaj +2 more sources
An Update on the Morphology and Phylogeny of the Nanoplanktonic Dinoflagellate Prorocentrum nux. [PDF]
ABSTRACT The Prorocentrales are a diverse group of dinophytes found in a wide range of marine environments. However, species delimitation in the genus Prorocentrum still remains a challenge, especially for nanoscale species where morphological and molecular information is often incomplete.
Mordret S +4 more
europepmc +2 more sources
How Does Climate Change Influence the Regional Ecological-Social Risks of Harmful Dinoflagellates? A Predictive Study of China's Coastal Waters. [PDF]
Climate change is expected to shift the risks posed by harmful dinoflagellates in China's coastal waters. In this study, the ecological–social risk is assessed by considering both the potential presence of these algae and their overlap with coastal populations and mariculture areas.
Su S +11 more
europepmc +2 more sources
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core +19 more sources

