Results 91 to 100 of about 71,717 (339)
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li +17 more
wiley +1 more source
A criança e a prosódia: uma retrospectiva e novos desenvolvimentos
This is a retrospective of my former work on the acquisition of prosody and specifically the role of the double face of prosody in acquisition is revisited.
Ester Mirian Scarpa
doaj +1 more source
Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li +8 more
wiley +1 more source
Background : The recognition of the emotion expressed during conversation relies on the integration of both semantic processing and decoding of emotional prosody. The integration of both types of elements is necessary for social interaction. No study has
Perrine eBrazo +7 more
doaj +1 more source
Auditory Processing Disorders in Elderly Persons vs. Linguistic and Emotional Prosody [PDF]
Anna Rasmus, Aleksandra Błachnio
openalex +1 more source
Chronic myeloid leukemia blast phase (CML‐BP) poses a severe therapeutic challenge. This study reveals that the super‐enhancer‐driven transcription factors SOX4 and SMAD3 form a cooperative axis critical for disease progression. They co‐activate the oncogenic kinase AXL and promote phospholipid remodeling via LPCAT1 to facilitate its signaling ...
Enzhe Lou +22 more
wiley +1 more source
We aimed to progress understanding of prosodic emotion expression by establishing brain regions active when expressing specific emotions, those activated irrespective of the target emotion, and those whose activation intensity varied depending on ...
Rachel L. C. Mitchell +3 more
doaj +1 more source
AI‐Optimized Vanadium Oxide Multilayers for More Than 20‐fold Enhancement in Bolometric Performance
Machine‐learning‐optimized WxV1‐xOy multilayer thin films with graded doping achieve a high TCR (7.3 % K−1), reduced hysteresis, and low noise under CMOS‐compatible growth conditions. This approach overcomes the long‐standing trade‐off in microbolometers between linear response and performance, offering a universal bolometric parameter greatly enhanced
Jin‐Hyun Choi +8 more
wiley +1 more source
In Situ Characterisation of Hydrogels via Dynamic Interface Printing
ABSTRACT Hydrogels have become pivotal materials for tissue engineering, robotics, biomedical devices, and sensing applications due to their diverse material compositions and tunable mechanical properties. While significant effort has focused on developing novel manufacturing approaches such as extrusion bioprinting and light‐based fabrication methods,
Callum Vidler +2 more
wiley +1 more source
CACNA1C risk variant affects microstructural connectivity of the amygdala
Deficits in perception of emotional prosody have been described in patients with affective disorders at behavioral and neural level. In the current study, we use an imaging genetics approach to examine the impact of CACNA1C, one of the most promising ...
Katharina Koch +8 more
doaj +1 more source

