Results 171 to 180 of about 263,903 (318)

Assessment of the PROSPECT safety systems including socio-economic evaluation [Elektronisk resurs]

, 2018
This report provides a new methodology for safety benefit assessment of real-world benefit of the Advanced Driver Assistance Systems (ADAS) in terms of saved lives and prevented injuries as well as the resulting monetary benefit for society.
Stoll, Johann,, Bálint, András,, Jaussein, Marie,, Schneider, Anja,, Bräutigam, Julia,, Petersson, Mats,, Perlet, Klaus,, Breunig, Sandra,, Kovaceva, Jordanka,, Puente Guillen, Pablo,, Large, David,, Schindler, Ron,   +11 more
core  

Personalised neoadjuvant therapy, based on tumour characteristics and patient choice, is the best way forward in rectal cancer. [PDF]

J Gastrointest Oncol
Sammour T.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Bank Risk-Taking in a Prospect Theory Framework Empirical Investigation in the Emerging Markets’ Case [PDF]

The purpose of this paper is to investigate the validity of some behavioral conjectures as alternative explanations of bank risk-taking behavior. We especially focus on the different valuation of gains and losses relative to a reference point, and the ...
Christophe Godlewski
core  

Top-down motivation both decreases and increases feature interference following a saccade. [PDF]

Psychon Bull Rev
Chiu TY, Golomb JD.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Do Fishermen Have Different Attitudes Toward Risk? An Application of Prospect Theory to the Study of Vietnamese Fishermen

Field experiment and household survey data are combined to investigate whether working in a risky occupation such as fishing makes fishermen have different risk preferences than individuals in other occupations.
Nguyen, Quang, Leung, PingSun
core  

The Canine Search and Adoption Decision Process: A Conceptual Framework for Companion Pet Shelter Adoption. [PDF]

Animals (Basel)
Minnis L, Davis DB.
europepmc   +1 more source

Prospects for the childless.

The St. Luke's Hospital gazette, 1976
The sorry plight of infertile couples has attracted the interest of the author for several years. His experience suggests that their silent suffering deserves to be shared and relieved. In private practice between 1969 and 1975 his records show that 332 couples sought advice about their infertility, an average of 47 per year. Yet so many of them seemed
openaire   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source