Results 51 to 60 of about 263,903 (318)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Prospect Theory Goes to War: Loss-Aversion and the Duration of Military Combat [PDF]
, 1997 This paper contributes to the empirical foundation of prospect theory in real-life international relations by testing two of its major implications in the field of military conflict. Using duration analysis for a data set of twentieth century battles, it
Thomas Bauer +3 more
core +1 more source
Domestic Resource Mobilisation for Sustainable Healthcare Financing in Nigeria: A Review
Nigerian Postgraduate Medical JournalDomestic resource mobilisation (DRM) is vital for achieving sustainable healthcare financing in Nigeria, where dependence on external funding and oil revenues has long hindered health sector progress.
Amina Idris Bello +3 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 Analysis of the batch issued data of Chinese vaccines from 2011 to 2020 showed that the average annual dose of vaccines in China was 769.66 million doses, and the overall production was stable.
Guanjie Wang, Mingli Shao
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Advances in Anther Culture-Based Rice Breeding in China
PlantsThe anther culture-based breeding of rice is a plant tissue culture technique that utilizes rice pollen to rapidly obtain haploid plants. In comparison with traditional breeding methods, this technique shortens the breeding cycle and enables the quick ...
Xinxing Chen +6 more
doaj +1 more source
PROSPEK DAN TANTANGAN USAHATANI TEMBAKAU MADURA
Sepa, 2017 Tobacco has an important role in the socio-economic life of the community, such as the State in the form of tax revenue and foreign exchange earnings,employment, the income of farmers, laborers, and merchants, as well as ...
Fuad Hasan, Dwidjono Hadi Darwanto
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source