Results 61 to 70 of about 311,944 (266)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Xiehe Yixue ZazhiWith the rapid development of the interdisciplinary area of artificial intelligence and medicine, large language model (LLM) has been widely used in the fields such as diagnosis and treatment, medicine, and healthcare.
CHEN Zijia +4 more
doaj +1 more source
Research development and prospect of mixed silage
Siliao yanjiu, 2021 Mixed silage is the fermentationof several raw materials in an anaerobic environment, which is complementary in composition and can better preserve the nutritional value. Mixed silages can provide better quality silage for animals, and can also increases
Lei ZHANG +5 more
doaj
Evolutionary Stability of Prospect Theory Preferences [PDF]
We demonstrate that in simple 2 X 2 games (cumulative) prospect theory preferences can be evolutionarily stable, i.e. a population of players with prospect theory preferences can not be invaded by more rational players.
Marc Oliver Rieger
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Microneedle-Mediated Treatment of Obesity
PharmaceuticsObesity has become a major public health threat, as it can cause various complications such as diabetes, cardiovascular disease, sleep apnea, cancer, and osteoarthritis.
Huanhuan Pan +9 more
doaj +1 more source
Research progress and application prospect of potato pulp feeding
Siliao yanjiu, 2021 Potato starch pulp is rich in nutrients, low cost and high yield, which is a good feed source. The feeding value of potato was analyzed. The feeding research status of potato residue was summarized from silage and fermentation.
Xin-juan WU
doaj
Risk Aversion in Cumulative Prospect Theory [PDF]
This paper characterizes the conditions for risk aversion in cumulative prospect theory where risk aversion is defined in the strong sense (Rothshild Stiglitz 1970).
Horst Zank, Schmidt, Ulrich
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
现状、挑战和展望：中国卒中急救地图 The Current Status, Challenges and Prospects of Stroke Emergency Map in China
Zhongguo cuzhong zazhi卒中是中国居民致死致残的主要原因，给社会带来了极重的负担。面对这一严峻的卒中救治形势，卒中急救地图应运而生。卒中急救地图通过地理信息系统和人工智能等先进技术整合医疗资源，构建了涵盖急救、转运、治疗到康复全流程的卒中救治网络，可较为显著地提升卒中的急救效率并改善患者预后。作为创新技术平台，卒中急救地图在提升卒中急救效率和治疗效果方面至关重要。目前，中国卒中急救地图取得初步成效，且发展态势良好，然而在实际应用中，仍然面临一些重要挑战。为了更好地发挥地图的作用，未来的研究应着眼于如何完善这一平台，加强推广 ...
曹黎明1，廖雨琦1，2，池枫1，3，任力杰1，3 (CAO Liming1, LIAO Yuqi1,2, CHI Feng1,3, REN Lijie1,3 )
doaj +1 more source