Results 81 to 90 of about 311,944 (266)
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Prospect House Princeton University
Since 1968, Prospect House has served as a dining and reception facility for faculty and staff, overlooking a lush, five-acre garden. This national historic landmark has an engaging background--the original stone farmhouse hosted several sessions of the ...
Beards, Daniel E.
core +2 more sources
Advances in drug delivery systems for the management of gout and hyperuricemia
Gout and hyperuricemia represent significant global health burdens, characterized by painful inflammatory arthritis and systemic metabolic dysfunction, respectively.
Zining Peng +15 more
doaj +1 more source
Local Status and Prospect Theory [PDF]
People are sometimes risk-averse in gains but risk-loving in losses. Such behavior and other anomalies underlying prospect theory arise from a model of local status maximization in which consumers compare their wealth with other consumers of similar ...
Rick Harbaugh, Tatiana Kornienko
core
Models of radiative transfer (RT) are important tools for remote sensing of vegetation, allowing for forward simulations of remotely sensed data as well as inverse estimation of biophysical and biochemical traits from vegetation optical properties ...
Feret, J-B (15534149) +3 more
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
China’s roof-cutting and pressure relief gob-side entry retaining (RCPR-GER) technology provides an efficient non-pillar mining solution that significantly enhances coal recovery.
Dong Duan +7 more
doaj +1 more source
Quantitative data denoting the number of active volunteers in City of Prospect and the hours they ...
core
Why Do People Pay Taxes? Prospect Theory Versus Expected Utility Theory [PDF]
Tax evasion analysis is typically based on an expected utility theory (EUT) framework. However, this leads to several qualitative and quantitative puzzles.
Sanjit Dhami, Ali al-Nowaihi
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

