Results 81 to 90 of about 263,903 (318)
Development and Prospect of Intra-Articular Injection in the Treatment of Osteoarthritis: A Review
Journal of Pain Research, 2020 Yin Zhang,1,2 Xinji Chen,1 Yu Tong,3 Junchao Luo,3 Qing Bi1,2 1Department of Orthopedic Surgery, Zhejiang Provincial People’s Hospital and People’s Hospital of Hangzhou Medical College, Hangzhou, Zhejiang 310014, People’s Republic of ...
Zhang Y, Chen X, Tong Y, Luo J, Bi Q
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Risk Aversion in Cumulative Prospect Theory [PDF]
This paper characterizes the conditions for risk aversion in cumulative prospect theory where risk aversion is defined in the strong sense (Rothshild Stiglitz 1970).
Horst Zank, Schmidt, Ulrich
core
From Lab to Life: Self‐Powered Sweat Sensors and Their Future in Personal Health Monitoring
Advanced ScienceThe rapid development of wearable sweat sensors has demonstrated their potential for continuous, non‐invasive disease diagnosis and health monitoring.
Nan Gao +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The Prospects for Sufficientarianism [PDF]
Utilitas, 2012 Principles of sufficiency are widely discussed in debates about distributive ethics. However, critics have argued that sufficiency principles are vulnerable to important objections. This article seeks to clarify the main claims of sufficiency principles and to examine whether they have something distinctive and plausible to offer.
openaire +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Assessment of the police officer profile in the post-agreement era in Colombia
RHS Revista Humanismo y Sociedad, 2017 Currently, after the peace agreement was signed between the Colombian government and the FARC-EP, Colombia is going through a historic moment that will certainly bring about changes, both directly and indirectly, for its public institutions as well as in
Natalia Pérez Puerta
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Prospect Theory or Skill Signaling? [PDF]
Failure is embarrassing. In gambles involving both skill and chance, we show that a strategic desire to avoid appearing unskilled generates behavioral anomalies that are typically explained by prospect theory’s concepts of loss aversion, probability ...
Rick Harbaugh
core