Results 81 to 90 of about 311,944 (266)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Prospect House Princeton University

open access: yes, 2008
Since 1968, Prospect House has served as a dining and reception facility for faculty and staff, overlooking a lush, five-acre garden. This national historic landmark has an engaging background--the original stone farmhouse hosted several sessions of the ...
Beards, Daniel E.
core   +2 more sources

Advances in drug delivery systems for the management of gout and hyperuricemia

open access: yesFrontiers in Pharmacology
Gout and hyperuricemia represent significant global health burdens, characterized by painful inflammatory arthritis and systemic metabolic dysfunction, respectively.
Zining Peng   +15 more
doaj   +1 more source

Local Status and Prospect Theory [PDF]

open access: yes
People are sometimes risk-averse in gains but risk-loving in losses. Such behavior and other anomalies underlying prospect theory arise from a model of local status maximization in which consumers compare their wealth with other consumers of similar ...
Rick Harbaugh, Tatiana Kornienko
core  

PROSPECT-PRO for estimating content of nitrogen-containing leaf proteins and other carbon-based constituents

open access: yes, 2021
Models of radiative transfer (RT) are important tools for remote sensing of vegetation, allowing for forward simulations of remotely sensed data as well as inverse estimation of biophysical and biochemical traits from vegetation optical properties ...
Feret, J-B (15534149)   +3 more
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Development Status and Prospect of Roof-Cutting and Pressure Relief Gob-Side Entry Retaining Technology in China

open access: yesApplied Sciences
China’s roof-cutting and pressure relief gob-side entry retaining (RCPR-GER) technology provides an efficient non-pillar mining solution that significantly enhances coal recovery.
Dong Duan   +7 more
doaj   +1 more source

City of Prospect Volunteers

open access: yes
Quantitative data denoting the number of active volunteers in City of Prospect and the hours they ...

core  

Why Do People Pay Taxes? Prospect Theory Versus Expected Utility Theory [PDF]

open access: yes
Tax evasion analysis is typically based on an expected utility theory (EUT) framework. However, this leads to several qualitative and quantitative puzzles.
Sanjit Dhami, Ali al-Nowaihi
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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