Results 41 to 50 of about 2,421,891 (317)

Collaborative overview ('meta-analysis') of prospective observational studies of the associations of usual blood pressure and usual cholesterol levels with common causes of death: protocol for the second cycle of the Prospective Studies Collaboration

, 1999
BACKGROUND: Many prospective studies have been reported on the associations of blood pressure and blood cholesterol with cardiovascular disease, but few have been large enough to provide reliable estimates of the nature of these associations in different
Prospective, Studies Collaboration
core   +2 more sources

Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

Nature Communications, 2019
Here, Thorsen et al. examine the microbiota during the first three months of life in a cohort of 700 children and find that microbial diversity and the relative abundances of Veillonella and Prevotella in the airways at one month of age are associated ...
Jonathan Thorsen, Morten A. Rasmussen, Johannes Waage, Martin Mortensen, Asker Brejnrod, Klaus Bønnelykke, Bo L. Chawes, Susanne Brix, Søren J. Sørensen, Jakob Stokholm, Hans Bisgaard   +10 more
doaj   +1 more source

L’épidémie de poliomyélite de 1948-1949 : chamanisme, force vitale et auto-sacrifice chez les Inuit du Kivalliq

Revue d'Études Autochtones, 2022
À l’automne 1948, une « maladie étrange » fait son apparition à Igluligaarjuk (Chesterfield Inlet), un petit village de la baie d’Hudson. Les Soeurs Grises en charge de l’hôpital sont les premières à sonner l’alerte.
Frédéric Laugrand
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

The impact of Eysenck's extraversion-introversion personality dimension on prospective memory

, 2001
Prospective memory (PM) is memory for future events. PM is a developing area of research (e.g., Brandimonte, Einstein & McDaniel, 1996) with recent work linking personality types and their utilisation of PM (Goschke & Kuhl, 1996; Searleman, 1996).
Heffernan, Tom, Ling, Jonathan
core   +1 more source

Longitudinal metabolome profiling from pregnancy through childhood and risk of neurodevelopmental disorders at age 10

Nature Communications
Neurodevelopmental disorders (NDD) are characterized by impairments in brain development that affect motor and cognitive systems. Early identification of NDD risk factors is crucial for prevention.
Tingting Wang, Jens Richardt Møllegaard Jepsen, Rebecca Vinding, Nicklas Brustad, Liang Chen, María Hernández-Lorca, Mina Ali, Julie Bøjstrup Rosenberg, Parisa Mohammadzadeh, Michael Widdowson, Parvaneh Ebrahimi, Morten A. Rasmussen, Jonathan Thorsen, Klaus Bønnelykke, Bjørn H. Ebdrup, Bo Chawes   +15 more
doaj   +1 more source

The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review

Metabolites, 2020
Asthma, allergic rhinitis, food allergy, and atopic dermatitis are common childhood diseases with several different underlying mechanisms, i.e., endotypes of disease.
Mette S. Schjødt, Gözde Gürdeniz, Bo Chawes   +2 more
doaj   +1 more source

Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohortResearch in context

EBioMedicine, 2023
Summary: Background: Exposure to perfluoroalkyl substances may affect offspring immune development and thereby increase risk of childhood asthma, but the underlying mechanisms and asthma phenotype affected by such exposure is unknown.
Astrid Sevelsted, Casper-Emil Tingskov Pedersen, Gözde Gürdeniz, Morten Arendt Rasmussen, Jörg Schullehner, Kalliroi Sdougkou, Jonathan W. Martin, Jessica Lasky-Su, Andreanne Morin, Carole Ober, Ann-Marie Malby Schoos, Jakob Stokholm, Klaus Bønnelykke, Bo Chawes, Hans Bisgaard   +14 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source