Results 81 to 90 of about 2,421,891 (317)

Prophages in the infant gut are pervasively induced and may modulate the functionality of their hosts

open access: yesnpj Biofilms and Microbiomes
Gut microbiome (GM) composition and function is pivotal for human health and disease, of which the virome’s importance is increasingly recognised. However, prophages and their induction patterns in the infant gut remain understudied.
Tamsin A. Redgwell   +12 more
doaj   +1 more source

On the prospects of longtermism

open access: yesBioethics
AbstractThis article objects to two arguments that William MacAskill gives in What We Owe the Future in support of optimism about the prospects of longtermism, that is, the prospects of positively influencing the longterm future. First, it grants that he is right that, whereas humans sometimes benefit others as an end, they rarely harm them as an end ...
Persson, I, Savulescu, J
openaire   +4 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Diminished time-based, but undiminished event-based, prospective memory among intellectually high-functioning adults with autism: Relation to working memory ability. [PDF]

open access: yes, 2013
Objective: Prospective memory (PM) is the ability to remember to carry out an intended action. Working memory is the ability to store information in mind while processing potentially distracting information.
Lind, Sophie E   +11 more
core   +1 more source

Faire comme si et faire comme ça

open access: yesSwiss Journal of Sociocultural Anthropology, 2015
Through four empirical imitation situations collected in the daily life of a dairy farm in Wallonia, this article examines the differences and similarities made between breeders, their cows and his milking robot.
Séverine Lagneaux
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Spatiotemporal dynamics of cholera epidemics in Ethiopia: 2015–2021

open access: yesScientific Reports
Since the onset of the seventh cholera pandemic, Ethiopia has been affected by recurrent epidemics. However, the epidemiology of cholera in this country remains poorly understood.
Sandra Moore   +7 more
doaj   +1 more source

The Wild Ways of Conscious Will: What We Do, How We Do It, Why It Has Meaning

open access: yesFrontiers in Psychology, 2013
It is becoming increasingly mainstream to claim that conscious will is an illusion. This assertion is based on a host of findings that indicate conscious will does not share an efficient-cause relationship with actions.
J. Scott Jordan
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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