Results 1 to 10 of about 3,392,544 (337)

Azithromycin and high-dose vitamin D for treatment and prevention of asthma-like episodes in hospitalised preschool children: study protocol for a combined double-blind randomised controlled trial

BMJ Open, 2022
Introduction Previous randomised controlled trials (RCTs) suggest antibiotics for treating episodes of asthma-like symptoms in preschool children. Further, high-dose vitamin D supplementation has been shown to reduce the rate of asthma exacerbations ...
Klaus Bønnelykke, Hans Bisgaard, Jakob Stokholm, Bo Chawes, Julie Nyholm Kyvsgaard, Ulrik Ralfkiaer, Nilofar Følsgaard, Trine Mølbæk Jensen, Laura Marie Hesselberg, Ann-Marie M Schoos   +9 more
doaj   +1 more source

Cost of Illness in Young Children: A Prospective Birth Cohort Study

Children, 2021
Childhood illness is extremely common and imposes a considerable economic burden on society. We aimed to quantify the overall economic burden of childhood illness in the first three years of life and the impact of environmental risk factors. The study is
Sarah Kristine Nørgaard, Nadja Hawwa Vissing, Bo Lund Chawes, Jakob Stokholm, Klaus Bønnelykke, Hans Bisgaard   +5 more
doaj   +1 more source

Handgrip strength associates with effort-dependent lung function measures among adolescents with and without asthma

Scientific Reports, 2023
Studies have shown association between handgrip strength (HGS) and FEV1, but the importance of this in relation to asthma pathophysiology and diagnostics remains unclear. We investigated the relationship between HGS and lung function metrics and its role
Laura Marie Hesselberg, Julie Nyholm Kyvsgaard, Jakob Stokholm, Hans Bisgaard, Klaus Bønnelykke, Bo Chawes   +5 more
doaj   +1 more source

The developing airway and gut microbiota in early life is influenced by age of older siblings

Microbiome, 2022
Background Growing up with siblings has been linked to numerous health outcomes and is also an important determinant for the developing microbiota.
Emil Dalgaard Christensen, Mathis Hjort Hjelmsø, Jonathan Thorsen, Shiraz Shah, Tamsin Redgwell, Christina Egeø Poulsen, Urvish Trivedi, Jakob Russel, Shashank Gupta, Bo L. Chawes, Klaus Bønnelykke, Søren Johannes Sørensen, Morten Arendt Rasmussen, Hans Bisgaard, Jakob Stokholm   +14 more
doaj   +1 more source

Childhood asthma is associated with development of type 1 diabetes and inflammatory bowel diseases: a Danish nationwide registry study

Scientific Reports, 2022
Asthma and autoimmune disorders might be affected by opposing immune mechanisms, T helper cells type 2 (Th2) and T helper cells type 1 (Th1) immunity, respectively. Knowledge on comorbidity can increase understanding of the underlying etiologies.
Mie Sylow Liljendahl, Astrid Sevelsted, Bo L. Chawes, Jakob Stokholm, Klaus Bønnelykke, Zorana Jovanovic Andersen, Hans Bisgaard   +6 more
doaj   +1 more source

The airway microbiota of neonates colonized with asthma-associated pathogenic bacteria

Nature Communications, 2023
Culture techniques have associated colonization with pathogenic bacteria in the airways of neonates with later risk of childhood asthma, whereas more recent studies utilizing sequencing techniques have shown the same phenomenon with specific anaerobic ...
Jonathan Thorsen, Xuan Ji Li, Shuang Peng, Rikke Bjersand Sunde, Shiraz A. Shah, Madhumita Bhattacharyya, Casper Sahl Poulsen, Christina Egeø Poulsen, Cristina Leal Rodriguez, Michael Widdowson, Avidan Uriel Neumann, Urvish Trivedi, Bo Chawes, Klaus Bønnelykke, Hans Bisgaard, Søren J. Sørensen, Jakob Stokholm   +16 more
doaj   +1 more source

Prospective Cohort Studies [PDF]

European Journal of Vascular and Endovascular Surgery, 2016
n ...
openaire   +3 more sources

Bell’s Palsy: A Prospective Study [PDF]

International Journal of Dentistry, 2020
Background. Bell’s palsy is an acute idiopathic facial nerve paralysis of sudden onset. It is the most common cause of lower motor neuron facial nerve paralysis with an annual incidence of 15–30 per 100,000 population. The objective of this work is to study the grade of the attack and the associated symptoms of Bell’s palsy in a group of Sudanese ...
Ahmed Hassan Kamil Mustafa, Ahmed Mohammed Suleiman   +1 more
openaire   +3 more sources

Exposures to perfluoroalkyl substances and asthma phenotypes in childhood: an investigation of the COPSAC2010 cohortResearch in context

EBioMedicine, 2023
Summary: Background: Exposure to perfluoroalkyl substances may affect offspring immune development and thereby increase risk of childhood asthma, but the underlying mechanisms and asthma phenotype affected by such exposure is unknown.
Astrid Sevelsted, Casper-Emil Tingskov Pedersen, Gözde Gürdeniz, Morten Arendt Rasmussen, Jörg Schullehner, Kalliroi Sdougkou, Jonathan W. Martin, Jessica Lasky-Su, Andreanne Morin, Carole Ober, Ann-Marie Malby Schoos, Jakob Stokholm, Klaus Bønnelykke, Bo Chawes, Hans Bisgaard   +14 more
doaj   +1 more source

Chrysotherapy. A prospective study [PDF]

Arthritis & Rheumatism, 1976
AbstractA 4‐year prospective clinical study of chrysotherapy was designed to reexamine old beliefs and traditions, and to test potentially new approaches to chrysotherapy. The standard weekly dosage of 50 mg was compared to that based on 1 mg/kg body weight; no significant differences were found.
N O, Rothermich, V K, Philips, W, Bergen, M H, Thomas   +3 more
openaire   +2 more sources