Results 91 to 100 of about 3,392,544 (337)

Socioeconomic status as a risk factor for dementia death:individual participant meta-analysis of 86 508 men and women from the UK [PDF]

, 2013
Background Life-course socioeconomic factors may have a role in dementia aetiology but there is a current paucity of studies. Meta-analyses of individual participant data would considerably strengthen this evidence base.
Cox, Emmanuel Stamatakis, Ferri, G. David Batty, John M. Starr, Mark Hamer, Marmot, Mika Kivimäki, MRC, Norton, Snowdon, Tom C. Russ, von Elm   +12 more
core   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Prophages in the infant gut are pervasively induced and may modulate the functionality of their hosts

npj Biofilms and Microbiomes
Gut microbiome (GM) composition and function is pivotal for human health and disease, of which the virome’s importance is increasingly recognised. However, prophages and their induction patterns in the infant gut remain understudied.
Tamsin A. Redgwell, Jonathan Thorsen, Marie-Agnès Petit, Ling Deng, Gisle Vestergaard, Jakob Russel, Bo Chawes, Klaus Bønnelykke, Hans Bisgaard, Dennis S. Nielsen, Søren Sørensen, Jakob Stokholm, Shiraz A. Shah   +12 more
doaj   +1 more source

Monitoring HSP70 exosomes in cancer patients’ follow up: a clinical prospective pilot study [PDF]

, 2020
Gaëtan Chanteloup, Marine Cordonnier, Nicolás Isambert, Aurélie Bertaut, Alice Hervieu, Audrey Hennequin, Maxime Luu, Sylvie Zanetta, Bruno Coudert, Leila Bengrine, Isabelle Desmoulins, Laure Favier, Aurélie Lagrange, P Pagès, Ivan M. Gutierrez, Jeanine Lherminier, Laure Avoscan, Clémentine Jankowski, Cédric Rébé, Angélique Chevriaux, Marie‐Martine Padeano, Charles Coutant, Sylvain Ladoire, Sylvain Causeret, Laurent Arnould, Céline Charon‐Barra, Vanessa Cottet, Julie Blanc, Christine Binquet, Marc Bardou, Carmen Garrido, Jessica Gobbo   +31 more
openalex   +1 more source

Body mass index and risk of non-alcoholic fatty liver disease: two electronic health record prospective studies [PDF]

, 2015
Context: The relationship between rising body mass index (BMI) and prospective risk of non-alcoholic fatty liver disease (NAFLD) / non-alcoholic steatohepatitis (NASH) is virtually absent. Objective: Determine the extent of the association between BMI
Bonato, Vinicius, Desai, Jigar, Gill, Jason M.R., Hyde, Craig, Kabadi, Shaum, Loomis, A. Katrina, Preiss, David, Sattar, Naveed, St. Louis, Matthew, Waterworth, Dawn, Welsh, Paul   +10 more
core   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Associations of the gut microbiome and inflammatory markers with mental health symptoms: a cross-sectional study on Danish adolescents

Scientific Reports
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that often persists into adulthood and is accompanied by comorbid mental health problems.
Aisha Alayna Brown, Michael Widdowson, Sarah Brandt, Parisa Mohammadzadeh, Julie B. Rosenberg, Jens Richardt Møllegaard Jepsen, Bjørn H. Ebdrup, María Hernández-Lorca, Klaus Bønnelykke, Bo Chawes, Jakob Stokholm, Jonathan Thorsen, Parvaneh Ibrahimi, Xuanji Li, Søren Johannes Sørensen, Morten Arendt Rasmussen   +15 more
doaj   +1 more source

Creatività e Tic nella scuola dell'obbligo: un'inchiesta su opinioni e pratiche degli insegnanti

Italian Journal of Educational Technology, 2010
La creatività è un’abilità fondamentale per lo sviluppo delle capacità di pensiero ed ha risvolti diretti e positivi sull’apprendimento. Spesso la creatività è interpretata in maniera limitata e non è necessariamente una priorità delle pratiche educative.
Anusca Ferrari
doaj   +1 more source

Internet Prospective Study

Bulletin of Electrical Engineering and Informatics, 2017
The Internet is currently the largest network of communication worldwide and is where technological advances could be observed. The original creation of the Internet was based on the idea that this network would be formed mainly by multiple independent networks with an arbitrary design.
Jesus Antonio Alvarez-Cedillo, Elizabeth Acosta Gonzaga, Mario Aguilar-Fernández, Patricia Perez-Romero   +3 more
openaire   +2 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source