Results 111 to 120 of about 3,209,681 (306)

Catalytic polymeric nanoreactors : more than a solid supported catalyst [PDF]

, 2012
Polymeric nanostructures can be synthesized where the catalytic motif is covalently attached within the core domain and protected from the environment by a polymeric shell.
Bosman, Liu, Wang, Yan
core   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

The European prospective osteoporosis study

Osteoporosis International, 1996
The objectives of the European Prospective Osteoporosis Study (EPOS) are to identify the causes of the current epidemic of hip and spine fractures affecting Europe and most other continents, with the possible exception of sub-Saharan Africa [1]. They cause much suffering and cost each family in the EU about 60 Ecu/ year.
openaire   +2 more sources

Sexually transmitted infection as a risk factor for homosexual HIV transmission: a systematic review of epidemiological studies

, 2000
Existing reviews suggest some sexually transmitted infections (STIs) are risk factors in heterosexual HIV transmission. This may not be so in homosexual HIV transmission, about which reviews make no specific conclusions.
Bonell, C, Hickson, F, Weatherburn, P
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Employing social accounting matrix multipliers to profile the bioeconomy in the EU member states: is there a structural pattern?

Spanish Journal of Agricultural Research, 2014
The concept of 'bioeconomy' is gathering momentum in European Union (EU) policy circles as a sustainable model of growth to reconcile continued wealth generation and employment with bio-based sustainable resource usage.
George Philippidis, Ana I. Sanjuán, Emanuele Ferrari, Robert M'barek   +3 more
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Looking Back at Prospective Studies [PDF]

Academic Radiology, 2008
Gur's perspective article raises important points about analytic methods and the clinical inferences drawn from retrospective statistical analyses of prospective studies. Specifically, he associates three problems with the scientific methods of retrospective analyses: (1) using the parametric receiver-operating characteristic (ROC) curve and the area ...
openaire   +2 more sources

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Risk behaviours and non-atopic comorbidities of adolescents with asthmaKey message

World Allergy Organization Journal
Background: Risk behaviours, obesity, and neuropsychiatric comorbidity have been demonstrated in various chronic diseases but are less well described among adolescents with asthma.
Trine Mølbæk-Engbjerg, MD, Nilo Vahman, MD, Ph.D., Mina Ali, MSc, Ph.D., Frederikke Skov, MD, Rebecca Vinding, MD, Ph.D., David Horner, MD, Ph.D., Nicklas Brustad, MD, Ph.D., Jonathan Thorsen, MD, Ph.D., Ann-Marie M. Schoos, MD, Ph.D., DMSc, Jakob Stokholm, MD, Ph.D., Klaus Bønnelykke, MD, Ph.D., Bo Chawes, MD, Ph.D., DMSc   +11 more
doaj   +1 more source