Results 121 to 130 of about 3,392,544 (337)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Effects of n-3 Long-Chain Polyunsaturated Fatty Acid and Vitamin D Supplementation on Transcriptional Profiles of Human Lung Organoids

Metabolites
Background/Objectives: Randomized clinical trials (RCTs) suggest that n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) and high-dose vitamin D supplementation during pregnancy may protect against childhood asthma.
Mina Ali, Martin Steen Mortensen, Ole Bæk, Nicklas Brustad, Tingting Wang, Liang Chen, Min Kim, Casper-Emil Tingskov Pedersen, Trevor D. Lawley, Athanasios Pasias, Jakub Sedzinski, Jakob Stokholm, Klaus Bønnelykke, Bo Chawes   +13 more
doaj   +1 more source

Las preferencias discontinuas en los experimentos de elección: impacto en el cálculo de la prima de los programas agroambientales

Economía Agraria y Recursos Naturales, 2010
En los experimentos de elección se presupone que los individuos consideran todos los atributos que describen un bien a la hora de escoger su opción preferida. Sin embargo, existe evidencia de que los individuos pueden obviar algún atributo.
María Espinosa-Godet, Jesús Barreiro-Hurlé   +1 more
doaj   +1 more source

Prognostic Value of Novel Liquid Biomarkers in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Enzalutamide: A Prospective Observational Study [PDF]

, 2020
Guillemette E. Benoist, Inge M. van Oort, Emmy Boerrigter, Gerald W. Verhaegh, Onno van Hooij, Levi Groen, Frank Smit, Pieter de Mol, Paul Hamberg, Vincent O. Dezentjé, Niven Mehra, Winald R. Gerritsen, Diederik M. Somford, Nielka P. H. van Erp, Jack A. Schalken   +14 more
openalex   +1 more source

Fearless Friday: Venissa Ledesma

, 2016
This week we are celebrating the work of Venissa Ledesma ’19. Venissa is a sophomore at Gettysburg College from San Diego, California. She is an Environmental Studies major and a Peace and Justice Studies minor. Currently, Venissa is the president of the
Ledesma, Venissa
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Risk behaviours and non-atopic comorbidities of adolescents with asthmaKey message

World Allergy Organization Journal
Background: Risk behaviours, obesity, and neuropsychiatric comorbidity have been demonstrated in various chronic diseases but are less well described among adolescents with asthma.
Trine Mølbæk-Engbjerg, MD, Nilo Vahman, MD, Ph.D., Mina Ali, MSc, Ph.D., Frederikke Skov, MD, Rebecca Vinding, MD, Ph.D., David Horner, MD, Ph.D., Nicklas Brustad, MD, Ph.D., Jonathan Thorsen, MD, Ph.D., Ann-Marie M. Schoos, MD, Ph.D., DMSc, Jakob Stokholm, MD, Ph.D., Klaus Bønnelykke, MD, Ph.D., Bo Chawes, MD, Ph.D., DMSc   +11 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Structural and electronic properties of the graphene/Al/Ni(111) intercalation-like system

, 2011
Decoupling of the graphene layer from the ferromagnetic substrate via intercalation of sp metal has recently been proposed as an effective way to realize single-layer graphene-based spin-filter.
Boettcher, S., Dedkov, Yu. S., Generalov, A., Horn, K., Voloshina, E. N., Weser, M.   +5 more
core   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source