Results 121 to 130 of about 6,685 (245)

Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2‐Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging

Aging Cell, Volume 25, Issue 2, February 2026.
A schematic showing decreased PTGES2 farnesylation in granulosa cells compromises PGE2‐dependent cumulus expansion and oocyte maturation during ovarian aging. In young ovaries, PTGES2 farnesylation of GCs regulates the process of cumulus expansion and oocyte maturation by facilitating PGE2 production.
Sainan Zhang, Jiahui Qi, Chuanming Liu, Huidan Zhang, Bichun Guo, Die Wu, Yicen Liu, Xin Zhen, Yang Zhang, Nannan Kang, Jidong Zhou, Guijun Yan, Chaojun Li, Lijun Ding, Haixiang Sun   +14 more
wiley   +1 more source

The Role of Prostaglandins as Major Inflammatory Mediators in Colorectal Cancer. [PDF]

Int J Mol Sci
Macia Guardado M, Lutz V, Hengstschläger M, Dolznig H.   +3 more
europepmc   +1 more source

Blood Cell Mitochondrial Respiration Increases With Age and Varies by Sex in Healthy Adults

Aging Cell, Volume 25, Issue 2, February 2026.
Using samples from the San Diego Nathan Shock Center Clinical Cohort, we found that blood cell bioenergetic capacity is generally positively associated with age and sex dependent. These findings highlight the importance of biological context in bioenergetics research. Created in BioRender. Lab, M. (2025) https://BioRender.com/pvgt48f.
Howard J. Phang, Jaclyn Bergstrom, Benjamin Keri, Stephanie R. Heimler, Stephen Dozier, Lina M. Scandalis, David Wing, Daniel Moreno, Nina N. Sun, Anthony J. A. Molina   +9 more
wiley   +1 more source

Endogenous modulators in lung cancer. [PDF]

World J Clin Cases
Patel N, Patel V, Surani S.
europepmc   +1 more source

Tetra- and Pentacyclic Triterpene Acids from the Ancient Anti-inflammatory Remedy Frankincense as Inhibitors of Microsomal Prostaglandin E₂Synthase-1 [PDF]

, 2014
Moritz Verhoff, Stefanie Seitz, Michael Paul, Stefan M. Noha, Johann Jauch, Daniela Schuster, Oliver Werz   +6 more
openalex   +1 more source

Comparative efficacy of combination therapy including regenerative therapies versus monotherapy for erectile dysfunction: A systematic review and meta‐analysis

Andrology, Volume 14, Issue 2, Page 358-367, February 2026.
Abstract Background and objective The Current European Association of Urology guidelines do not provide recommendation for combination of regenerative therapies with standard therapies for erectile dysfunction. The aim of this study was to compare the efficacy of combined regenerative therapy with monotherapy for erectile dysfunction.
Alberto Quistini, Giuseppe Fallara, Marco Tozzi, Massimiliano Depalma, Rocco Damiano, Alessandro Palmieri, Fabio Castiglione, Andrea Salonia, Roberto Bianchi, Matteo Ferro, Asif Muneer, Hussain M. Alnajjar, Karl H. Pang   +12 more
wiley   +1 more source

Coordinate Functional Regulation between Microsomal Prostaglandin E Synthase-1 (mPGES-1) and Peroxisome Proliferator-activated Receptor γ (PPARγ) in the Conversion of White-to-brown Adipocytes [PDF]

, 2013
Verónica García‐Alonso, Cristina López‐Vicario, Esther Titos, Eva Morán‐Salvador, Ana González‐Périz, Bibiana Rius, Marcelina Párrizas, Oliver Werz, Vicente Arroyo, Joan Clària   +9 more
openalex   +1 more source

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Prostanoids in Liver Repair and Regeneration: Biosynthesis, Receptors, and Intercellular Communication. [PDF]

Cell Mol Gastroenterol Hepatol
Li X, Xu X, Lai W, Jiang A, Zhou N, Yu Y.   +5 more
europepmc   +1 more source

mPGES-1 (Microsomal Prostaglandin E Synthase-1) Mediates Vascular Dysfunction in Hypertension Through Oxidative Stress [PDF]

, 2018
María Soledad Avendaño, Ana B. García‐Redondo, Guillermo Zalba, María González‐Amor, Andrea Aguado, Sonia Martínez‐Revelles, Luis M. Beltrán, Mercedes Camacho, Victoria Cachofeiro, María J. Alonso, Mercedes Salaíces, Ana M. Briones   +11 more
openalex   +1 more source