Abstract High‐latitude ecosystems are simultaneously warming and acidifying under ongoing climate change. Arctic cod (Boreogadus saida) are a key species in the Arctic Ocean and have demonstrated sensitivity to ocean warming and acidification as adults and embryos, but their larval sensitivity to the combined stressors is unknown. In a laboratory multi‐
Emily Slesinger+6 more
wiley +1 more source
Microglia‐specific expression of microsomal prostaglandin E2 synthase‐1 contributes to lipopolysaccharide‐induced prostaglandin E2 production [PDF]
Yuri Ikeda‐Matsuo+5 more
openalex +1 more source
MRI‐based surrogates of brain clearance in narcolepsy type 1
Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese+6 more
wiley +1 more source
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi+6 more
wiley +1 more source
Is Adipose Tissue Inflammation the Culprit of Obesity‐Associated Comorbidities?
ABSTRACT In individuals with obesity, the onset of chronic comorbidities coincides with the excessive accumulation of adipose tissue in various tissue beds. As obesity progresses, adipose tissue becomes increasingly dysfunctional causing chronic low‐grade inflammation.
Laurent Turner+3 more
wiley +1 more source
Regulation and roles of the hyaluronan system in mammalian reproduction [PDF]
Afify+79 more
core +1 more source
Microsomal prostaglandin E synthase-1 (mPGES-1) is the primary form of PGES expressed by the primate periovulatory follicle [PDF]
Diane M. Duffy+2 more
openalex +1 more source
Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso+5 more
wiley +1 more source
Downregulation of Cytosolic Prostaglandin E2Synthase Results in Decreased Nociceptive Behavior in Rats [PDF]
Annette Hofacker+5 more
openalex +1 more source
Skin‐Derived PGD2 Promotes Antigen‐Specific IgE Production via CRTH2 Signaling
Allergy, EarlyView.
Misato Kida+5 more
wiley +1 more source