Results 181 to 190 of about 6,685 (245)

Tumor‐Derived Prostaglandin E2 Promotes Colorectal Cancer Progression by Inducing N2‐Type TAN Polarization

Cancer Science, Volume 117, Issue 1, Page 19-32, January 2026.
We demonstrated that PGE2 released from LDs in CRC cells plays important roles in N2‐type TANs polarization. PGE2 enters neutrophils through its receptor EP2/EP4 to stimulate ROS‐mediated FOXO3a methylation, thereby increasing the polarization of N2‐type TANs.
Yue Han, Wen Chen, Bin Zhang, Shuang Wang   +3 more
wiley   +1 more source

Colorectal Neoplasia Pathogenesis in Normal Appearing Colonic Mucosa -A Perspective With Focus on Eicosanoid Signaling Pathways. [PDF]

Cancer Med
Feddersen UR, Hendel SK, Berner-Hansen VH, Veedfald S, Berner-Hansen M, Bindslev N.   +5 more
europepmc   +1 more source

Sulforaphane Inhibits Prostaglandin E2 Synthesis by Suppressing Microsomal Prostaglandin E Synthase 1

, 2012
Jiping Zhou, Denise G. Joplin, Janet V. Cross, Dennis J. Templeton   +3 more
openalex   +2 more sources

Microsomal Prostaglandin E Synthase-1 in Osteoarthritis

, 2021
Tuure Lauri, Tuure Lauri
openaire   +1 more source

Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Ruchi Biswas, Jamie Moore Fried, Maria A. Curotto de Lafaille   +2 more
wiley   +1 more source

Effects of Acute and Chronic Cold Stress on Expression of Cyclooxygenase-2 and Prostaglandin E Synthase mRNA in Quail Intestine

, 2013
CP Liu J Fu
openalex   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

A combination of ethanol and arachidonic acid promotes steatosis and endoplasmic reticulum stress and impairs mitochondrial respiration in H9c2 cardiomyoblasts. [PDF]

Lipids Health Dis
Ai W, New E, Casey CA, Saraswathi V.
europepmc   +1 more source

Quercetin Alleviates Osteoarthritis Pain by Inhibiting Vascular Endothelial Growth Factor A Through Regulating cGAS/STING Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Knee osteoarthritis (KOA), a common degenerative joint disease marked by pain, inflammation and cartilage degradation, has been increasingly associated with dysregulated innate immune signalling. Among the implicated molecular pathways, cGAS/STING has emerged as a key modulator in both disease pathogenesis and therapeutic intervention ...
Enrui Hu, Yibao Wei, Taiyang Liao, Deren Liu, Zijian Gong, Jun Mao, Peimin Wang, Nongshan Zhang   +7 more
wiley   +1 more source

Neonatally-derived multipotent Islet-1+ Mesp1+FOXA2+ stem cell clones restore cardiac function in sheep. [PDF]

Front Cardiovasc Med
Hughes L, Baio J, Hasaniya N, Bailey L, Kim J, Yanez D, Austin E, Vega R, Rivera Morales P, Camberos V, Wilson CG, Veliz AL, Kearns-Jonker M.   +12 more
europepmc   +1 more source