Results 241 to 250 of about 78,509 (319)

Regulation of the microsomal prostaglandin E synthase‐1 in polarized mononuclear phagocytes and its constitutive expression in neutrophils

Journal of Leukocyte Biology, 2007
M. Mosca, N. Polentarutti, G. Mangano, C. Apicella, A. Doni, F. Mancini, M. De Bortoli, I. Coletta, L. Polenzani, G. Santoni, M. Sironi, A. Vecchi, A. Mantovani   +12 more
semanticscholar   +1 more source

Co-Overexpression of Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 Adversely Affects the Postoperative Survival in Non-small Cell Lung Cancer

, 2010
Yu–Chung Wu, Li Su, Hao‐Wei Wang, Chien-Fu Jeff Lin, Wen‐Hu Hsu, Teh‐Ying Chou, Chi‐Ying F. Huang, Chia-Li Lu, Chung-Tsen Hsueh   +8 more
openalex   +1 more source

The Interplay of Cross‐Organ Immune Regulation in Inflammation and Cancer

MedComm, Volume 6, Issue 7, July 2025.
Organs interact dynamically through immune regulation, influencing systemic immune responses and disease progression. We review molecular and cellular mechanisms of cross‐organ immune regulation in inflammation and cancer, focusing on gut, liver, and brain interactions with other organs.
Jie Dou, Jinzuo Jiang, Yangtao Xue, Xiaoqi Jiang, Yongzhuo Jiang, Peng Xiao, Junjie Xu   +6 more
wiley   +1 more source

Crisdesalazine alleviates inflammation in an experimental autoimmune encephalomyelitis multiple sclerosis mouse model by regulating the immune system. [PDF]

BMC Neurosci
Park SM, Oh YH, Lim GH, An JH, Lee JH, Gwag BJ, Won SJ, Seo KW, Youn HY.   +8 more
europepmc   +1 more source

Membrane-Bound Prostaglandin E Synthase-1-Mediated Prostaglandin E2 Production by Osteoblast Plays a Critical Role in Lipopolysaccharide-Induced Bone Loss Associated with Inflammation

Journal of Immunology, 2006
Masaki Inada, Chiho Matsumoto, S. Uematsu, S. Akira, C. Miyaura   +4 more
semanticscholar   +1 more source

Microsomal Prostaglandin E Synthase 1 Deletion Retards Renal Disease Progression But Exacerbates Anemia in Mice With Renal Mass Reduction

, 2011
Zhanjun Jia, Hai‐Ping Wang, Tianxin Yang   +2 more
openalex   +1 more source

Endoplasmic Reticulum Stress in Cancer

MedComm, Volume 6, Issue 7, July 2025.
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou, Wenlong Wang, Baizhao Li, Zhu Li, Juan Huang, Xinying Li   +5 more
wiley   +1 more source

Lipopolysaccharide-Induced Increase of Prostaglandin E2 Is Mediated by Inducible Nitric Oxide Synthase Activation of the Constitutive Cyclooxygenase and Induction of Membrane-Associated Prostaglandin E Synthase1

Journal of Immunology, 2001
Y. Devaux, C. Seguin, S. Grosjean, N. de Talancé, Viviane Camaeti, A. Burlet, F. Zannad, C. Meistelman, P. Mertes, D. Longrois   +9 more
semanticscholar   +1 more source

Lactate Metabolism and Lactylation Modification: New Opportunities and Challenges in Cardiovascular Disease

MedComm, Volume 6, Issue 7, July 2025.
Lactate, beyond a metabolic byproduct, regulates immunity and inflammation, linked to cardiovascular diseases (CVD) via metabolic reprogramming. Lactylation, a lactate‐driven epigenetic mark, modulates gene expression in fibrosis, lipid disorders, and CVD progression.
Mengyang Song, Bin Liu, Haiou Wang, Wei Sun   +3 more
wiley   +1 more source

Activation of the COX-2/mPGES-1/PGE-2 cascade through the NLRP3 inflammasome contributes to Angiostrongylus cantonensis-induced eosinophilic meningoencephalitis. [PDF]

Parasitol Res
Chen KM, Lu CY, Lai SC.
europepmc   +1 more source