Results 91 to 100 of about 63,527 (251)

Prostaglandin-inhibitor naproxen does not affect contact lens-induced changes in the human corneal endothelium

, 1984
A randomized, double-masked, placebo-controlled study was conducted to determine the effect of the prostaglandin-inhibitor naproxen on the bleb response of the corneal endothelium during hydrogel contact lens wear.
Holden, Brien A., Efron, Nathan, Vannas, Antti   +2 more
core  

Nuciferine Suppresses Inflammatory Hepatocarcinogenesis by Targeting cPLA2‐Dependent Arachidonic Acid Metabolism

Advanced Science, EarlyView.
Nuciferine directly binds the C2 domain of cPLA2, impairing its Ca2+‐dependent membrane translocation and activation. By suppressing arachidonic acid release and downstream pro‐inflammatory eicosanoid production, nuciferine attenuates NF‐κB signaling and inflammatory hepatocarcinogenesis, revealing cPLA2 as a direct molecular target underlying its ...
Jing Sun, Xinyan Wu, Shuwei Luo, Yilang Liu, Jie Liu, Jun Lu, Weimin Wang, Xiao Feng, Tuo Zhang, Dipak Panigrahy, Jianjun Deng, Xiaojun Liao, Haixia Yang   +12 more
wiley   +1 more source

Aglepristone efficiency with and without the canine pyometra cloprostenol

Revista Mvz Cordoba, 2015
Objective. Evaluate the effectiveness of aglepristone with and without cloprostenol for treating canine pyometra. Materials and methods. Ten female French Bulldogs between 3-8 years of age diagnosed with pyometra were divided into two groups, one ...
Víctor Molina D
doaj   +1 more source

Prostaglandin-associated periorbitopathy in latanoprost users

, 2014
Shunsuke Nakakura,1 Minamai Yamamoto,1 Etsuko Terao,1 Nozomi Nagatomi,1 Naoko Matsuo,1 Yausko Fujisawa,1 Yuki Fujio,1 Hitoshi Tabuchi,1 Yoshiaki Kiuchi2 1Department of Ophthalmology, Saneikai Tsukazaki Hospital, Himeji, Japan; 2Department of ...
Nakakura S, Yamamoto M, Nagatomi N, Kiuchi Y, Fujio Y, Tabuchi H, Terao E, Fujisawa Y, Matsuo N   +8 more
core  

In vitro effects of prostaglandin E1, prostaglandin I2 and papaverine on internal thoracic artery graft

, 2015
Background: This study aims to investigate the effects of prostaglandin E1, prostaglandin I2, and papaverine on internal thoracic artery grafts which are used during coronary artery bypass graft operations.
Guclu, Orkut, Canbaz, Suat, Huseyin, Serhat, Yuksel, Volkan, Misirlioglu, Ganime, Ege, Turan, Karadag, Hakan   +6 more
core   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao, Wei Feng, Wei Zong, Yi Li, Xinyue Qin, Xinyue Wang, Yubo Yang, Guanhua Chen, Yiting Hou, Xuan Tan, Lin Chen, Ming Zhang, Feng Wang   +12 more
wiley   +1 more source

Acute macular edema following intracorporeal prostaglandin injection for erectile dysfunction

, 2015
Masumi G Asahi, Calvin Chou, Ron P Gallemore Retina Macula Institute, Torrance, CA, USA Purpose: We aimed to describe the first case of macular edema following intracorporeal injection of alprostadil, a prostaglandin E1.
Asahi MG, Chou C, Gallemore RP
core  

Anatomy of Prostaglandin Signals

, 2011
An enzymatic step in prostaglandin synthesis plays a key role in neuroinflammation in the mammalian brain.
Nephi Stella
core   +1 more source

PTGIS (prostaglandin I2 (prostacyclin) synthase) [PDF]

, 2010
Review on PTGIS (prostaglandin I2 (prostacyclin) synthase), with data on DNA, on the protein encoded, and where the gene is ...
I Cebola, MA Peinado, Cebola, I, Peinado, MA   +3 more
core   +1 more source

Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses

Advanced Science, EarlyView.
Circulating polyethylene microplastic burden is positively associated with heightened ADHD symptom severity and systemic redox‐inflammatory imbalance in children. Mechanistic investigation in a developmental co‐exposure mouse model further demonstrates that microplastics aggravate ADHD‐like behaviors, dopaminergic dysregulation, and oxidative ...
Yufan Luo, Ruijin Xie, Hua Xu, Xue Xiao, Wei Xiao, Qiyang Pan, Shengjie Xu, Li Liu, Zeliang Xiao, Yue Zhou, Chenyu Sun, Yu Wu, Yueying Liu   +12 more
wiley   +1 more source