Results 81 to 90 of about 63,527 (251)

Real-World Study on Patient Satisfaction and Tolerability After Switching to Preservative-Free Latanoprost

Clinical Ophthalmology, 2021
Carl Erb,1 Ingeborg Stalmans,2 Milko Iliev,3 Francisco José Muñoz-Negrete4 1Eye Clinic Wittenbergplatz, Berlin, Germany; 2Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium; 3Ophthalmology Department, University of ...
Erb C, Stalmans I, Iliev M, Muñoz-Negrete FJ   +3 more
doaj  

Astrocytes Coordinate Neurovascular Coupling During Prolonged Sensory Demand via AQP4/TRPA1/BEST1/D‐Serine Signaling

Advanced Science, EarlyView.
Neuronal activation leads to astrocytic transient volume changes, activating transient receptor potential ankyrin 1 (TRPA1) channels, leading to Ca2+ influx. Activation of TRPA1 causes the release of D‐serine through BEST1. Finally, the augmented extracellular levels of D‐serine boost neuronal activity by binding GluN1‐containing NMDARs, leading to CBV
Kayoung Han, Minwoo Wendy Jang, Taeyoung Park, Ki Jung Kim, Victor James Drew, Sunpil Kim, Tai Young Kim, Mingu Gordon Park, Myeongju Kim, Seung Won Chung, Minah Suh, C. Justin Lee   +11 more
wiley   +1 more source

Aspergillus fumigatus effector crpA orchestrates host prostaglandin signaling to promote fungal virulence

mBio
Conidia are the primary infection structures in Aspergillus fumigatus, the etiologic agent of aspergillosis. Here, we characterized CrpA (a cysteine-rich protein), a conidial surface-associated protein important for fungal evasion and host immunity ...
Camila Figueiredo Pinzan, Camila Diehl, Patrícia Alves de Castro, Endrews Delbaje, Peter Rocha, Camila Langer Marciano, Nathalia Gonsales da Rosa-Garzon, Hamilton Cabral, Rosanne Sprute, Androniki Kolovou, Adriana Ferreira Lopes Vilela, Carlos Arterio Sorgi, Agathe Ecoutin, Mélanie Berbon, Antoine Loquet, Edismauro Garcia Freitas-Filho, Larissa Dias Cunha, Savini U. Thrikawala, Emily E. Rosowski, Thaila Fernanda dos Reis, Gustavo H. Goldman   +20 more
doaj   +1 more source

Molecular Landscapes of Tumor Dormancy in Gynecologic Malignancies: From Survival Mechanisms to Precision Interception

Advanced Science, EarlyView.
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng, Ren‐Wang Peng, Chang‐Cheng Wu, Chi‐Wen Luo, Emmanuel Naveen Raj, Zhi‐Hong Wen, Tzu‐Hung Hsiao, Chia‐Jung Li   +7 more
wiley   +1 more source

Sustained CREB Phosphorylation Is Associated with Neuritogenic Prostanoid Signaling in NSC-34 Cells

Cells
Neuritogenesis is essential for neuronal development and circuit formation. Although cAMP signaling downstream of Gs-coupled receptors is considered pro-neuritogenic, activation of these Gs-coupled receptors can produce divergent cellular outcomes.
Koume Nagayama, Hiroshi Nango, Komugi Tsuruta, Hiroko Miyagishi, Yasuhiro Kosuge   +4 more
doaj   +1 more source

Niacin, an old drug with a new twist

Journal of Lipid Research, 2013
Niacin (nicotinic acid) has been used for decades as a lipid-lowering drug. The clinical use of niacin to treat dyslipidemic conditions is limited by its side effects.
Wen-Liang Song, Garret A. FitzGerald
doaj   +1 more source

Cerebral arteriolar damage by arachidonic acid and prostaglandin G2

, 1980
Application of arachidonic acid or prostaglandin G(2) to the brain surface of anesthetized cats induced cerebral arteriolar damage. Scavengers of free oxygen radicals inhibited this damage.
Ellis, E F, Magiera, C J, Kontos, H A, Wei, E P, Povlishock, J T, Dietrich, W D   +5 more
core   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Prostaglandin dan Aspek Penggunaannya [PDF]

Berawal dari masalah kekurangan persediaan protein dalam mencukupi kebutuhan baku gizi maupun konsumsi bagi rakyat Indonesia, perlu suatu teknologi untuk pengembangan peternakan antara lain, pemakaian Prostaglandin untuk penyerentakan berahi, pengobatan ...
Seno Adji Nugroho, S
core   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

Advanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu, Lingling Xie, Wenyi Liu, Hanjie Mo, Chengshu Xie, Jing Tang, Zhaorui Wang, Peixuan Lan, Jianping Zhang, Jie Gao, Qionglan Tang, Chunwei Cao, Hui Chen   +12 more
wiley   +1 more source