Results 61 to 70 of about 348,697 (337)

Ultra‐Fine 3D Bioprinting of Dynamic Hyaluronic Acid Hydrogel for in Vitro Modeling

Advanced Materials, EarlyView.
3D bioprinting merges tissue engineering and additive manufacturing to create biological structures. A bioink is developed by modifying hyaluronic acid, a natural extracellular matrix polymer, with cysteine. Potassium iodide is later added to tune gelation kinetics, enabling fine printing with a 32G needle.
Shima Tavakoli, Aybike Kocatürkmen, Oommen P. Oommen, Oommen P. Varghese   +3 more
wiley   +1 more source

The Effects of Intrauterine Injection with Prostaglandin F2α, Arachidonic Acid and Phosphate Solution on the Eggshell Formation of Japanese Quail Hen

The Journal of Poultry Science, 2002
Inhibitory effects of prostaglandin F2α, arachidonic acid and phosphate solution on the eggshell formation were investigated in Japanese quail. All injections were performed intrauterinely 8h before the predicted oviposition. Prematurely oviposited
Tomoki Soh, Kiyoshi Yamamoto, Noboru Fujihara, Osamu Koga   +3 more
doaj   +1 more source

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source

Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole and decrease their microbicidal capacity against Toxoplasma gondii

Memorias do Instituto Oswaldo Cruz, 2014
Lipid bodies [lipid droplets (LBs)] are lipid-rich organelles involved in lipid metabolism, signalling and inflammation. Recent findings suggest a role for LBs in host response to infection; however, the potential functions of this organelle in ...
Laura Azeredo Miranda Mota, João Roberto Neto, Verônica Gomes Monteiro, Caroliny Samary Silva Lobato, Marco Antonio de Oliveira, Maura da Cunha, Heloisa D’Ávila, Sérgio Henrique Seabra, Patrícia Torres Bozza, Renato Augusto DaMatta   +9 more
doaj   +1 more source

An investigation on the possibility of using eCG for presynchronization prior to ovsynch in dairy cow [PDF]

Iranian Journal of Veterinary Medicine, 2018
Background: Presynchronization could enhance fertility in timed breeding programs. The best presynchronization method has to justify biological requirements and to provide practical and economic advantages.
Amir Niasari-Naslaji, Hadi Kavousi Nodar, Mahdi Vojgani, Farid Heidari   +3 more
doaj   +1 more source

Biosynthesis of Prostaglandins [PDF]

Annual Review of Nutrition, 1991
Highly purified cyclooxygenase from sheep vesicular glands is stimulated by the presence of protoporphyrin IX compounds. This stimulation may be due to the conversion of an apoenzyme to the holoenzyme, and full activity is achieved when half of the enzyme subunits (70,000 daltons) bind heme.
openaire   +3 more sources

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

A combined analysis of four observational studies evaluating the intraocular pressure-lowering ability and tolerability of bimatoprost 0.01% in patients with primary open-angle glaucoma or ocular hypertension

Clinical Ophthalmology, 2016
Annemie Stevens,1 Milko E Iliev,2 Leo de Jong,3 Ioana Grobeiu,4 Anton Hommer5 1Department of Ophthalmology, Ghent University Hospital, Ghent, Belgium; 2Department of Ophthalmology, University of Bern, Bern, Switzerland; 3Department of Ophthalmology ...
Stevens A, Iliev ME, de Jong L, Grobeiu I, Hommer A   +4 more
doaj  

Cyclooxygenase 2-Regulated Genes an Alternative Avenue to the Development of New Therapeutic Drugs for Colorectal Cancer

Frontiers in Pharmacology, 2020
Colorectal cancer (CRC) is one of the most common and recurrent types of cancer, with high mortality rates. Several clinical trials and meta-analyses have determined that the use of pharmacological inhibitors of cyclooxygenase 2 (COX-2), the enzyme that ...
Alicia M. Hidalgo-Estévez, Konstantinos Stamatakis, Konstantinos Stamatakis, Marta Jiménez-Martínez, Ricardo López-Pérez, Manuel Fresno, Manuel Fresno   +6 more
doaj   +1 more source