Results 81 to 90 of about 348,697 (337)
Intravenous Epoprostenol for Management of Pulmonary Arterial Hypertension during Pregnancy
American Journal of Perinatology Reports, 2013 Background Pulmonary arterial hypertension carries a high risk of mortality in pregnancy. Recent advances in treatment may improve disease course and allow for successful management of the pregnancy.
Julia Timofeev +3 more
doaj +1 more source
Journal of Experimental Medicine, 2009 Prostaglandins, particularly prostaglandin E2 (PGE2), play an important role during inflammation. This is exemplified by the clinical use of cyclooxygenase 2 inhibitors, which interfere with PGE2 synthesis, as effective antiinflammatory drugs.
K. Boniface +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei +11 more
wiley +1 more source
Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation
Advanced Science, EarlyView.This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen +7 more
wiley +1 more source
Revista Colombiana de Obstetricia y Ginecología, 2009 Objetivos: revisar la asociación que existe entre los diferentes mecanismos inmunes y los eventos endocrinos necesarios para la regulación de la reproducción humana.
Ivonne Díaz-Yamal, Carolina Ruiz-Wagner
doaj
Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury
Advanced Science, EarlyView.Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley +1 more source
Prostaglandin E2 and pain--an update.
Biological and Pharmaceutical Bulletin, 2011 Prostaglandin E(2) (PGE(2)), a cyclooxygenase (COX) product, is the best known lipid mediator that contributes to inflammatory pain. Nonsteroidal anti-inflammatory drugs (NSAIDs), inhibitors of COX-1 and/or COX-2, suppress inflammatory pain by reducing ...
A. Kawabata
semanticscholar +1 more source
Advanced Science, EarlyView.This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang +8 more
wiley +1 more source
Preliminary investigation on antipyretic activity of Cuscuta Reflexa in rats
Journal of Advanced Pharmaceutical Technology & Research, 2010 In present study, the antipyretic activity of aqueous and ethanol extracts from Cuscuta reflexa Roxb. (Cuscutaceae) was evaluated using Brewer′s yeast induced pyrexia in rats.
Sanjib Bhattacharya, Bodhisattva Roy
doaj
Host Lipid Mediators in Leprosy: The Hypothesized Contributions to Pathogenesis
Frontiers in Immunology, 2018 The spectrum of clinical forms observed in leprosy and its pathogenesis are dictated by the host’s immune response against Mycobacterium leprae, the etiological agent of leprosy.
Carlos A. M. Silva, John T. Belisle
doaj +1 more source