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Papaverine plus prostaglandin E1 versus prostaglandin E1 alone for intracorporeal injection therapy
International Urology and Nephrology, 1998A study comparing intracorporeal injection of prostaglandin E1 (one-drug solution) and papaverine plus prostaglandin E1 (2-drug solution) for treatment of impotence.A total of 100 impotent patients had intracorporeal injections of the one-drug and 2-drug solution alternatively in 3 sessions.
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Leukocytosis caused by prostaglandin E1 in neonates
The Journal of Pediatrics, 2001We conducted a retrospective study of neonatal leukocytosis induced by prostaglandin E(1). Among 45 neonates with congenital heart disease, leukocyte counts increased during PGE(1) infusion. We conclude that PGE(1) infusion is a predictable cause of leukocytosis in newborns with congenital heart disease.
Henry C. Baggett +3 more
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Phosphatidylethanolamide derivatives of prostaglandins E1 and E2
Prostaglandins, 1976Prostaglandins E1 (PGE1) and E2 (PGE2) have been coupled with the amine group of phosphatidylethanolamine (PE) by means of dicyclohexylcarbodiimide. These complexes basically mimic the relaxant and contractile effects of the corresponding free prostaglandins (PGs) on various smooth muscle preparations, but exhibit a delayed onset of action and a lower ...
E. Bohn, H. Kunze, D. Le-Kim, R.B. Ghooi
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Acta Physiologica Scandinavica, 1966
(PGE1) Prostaglandin E1 was infused into anesthetized dogs to the aorta or (i.v.) intravenously in doses from 0.12-1.2 mcg/kg/minute. In all dogs a reproducible fall in blood pressure and increase in heart rate was obtained.
L. Carlson, L. Orö
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(PGE1) Prostaglandin E1 was infused into anesthetized dogs to the aorta or (i.v.) intravenously in doses from 0.12-1.2 mcg/kg/minute. In all dogs a reproducible fall in blood pressure and increase in heart rate was obtained.
L. Carlson, L. Orö
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Effects of prostaglandin E1 on renal hemodynamics
Journal of Anesthesia, 1994The glomerular filtration rate (GFR), renal plasma flow (RPF), renal blood flow (RBF), filtration fraction (FF), and the ratio of mean arterial pressure (MAP) to RBF (MAP/RBF), reflecting renal vascular resistance (RVR) were determined to investigate the effects of intravenously administered prostaglandin E1 (PGE1) on renal hemodynamics in humans. PGE1
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The preparation and characterization of prostaglandin E1 antiserum
Prostaglandins, 1974Abstract Antiserum against PGE1 was raised in rabbits following immunization with prostaglandin-thyroglobulin conjugates. The antiserum exhibits 22% cross reactivity with PGE2 but little or no apparent cross reaction with PGE1 metabolites or heterologous prostaglandins.
William A. Stylos +3 more
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On the action of prostaglandin E1 and prostaglandins from brain on the isolated rat stomach.
Canadian Journal of Physiology and Pharmacology, 1966Prostaglandins are a group of structurally related dihydroxyketo- and trihydroxy-C20 unsaturated carboxylic acids which cause contraction of intestinal smooth muscle at concentrations down to 1 × 10−10 g/ml.
F. Coceani, L. Wolfe
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A short synthesis of (−)-prostaglandin E1
Tetrahedron Letters, 1983Abstract (−)-Prostaglandin E1 has been prepared from ( R -4- t -butyldimethylsiloxy-2-cyclopentenone by using as a key operation the tandem organocopper conjguate addition/nitroolefin Michael trapping of the resulting enolate intermediate.
A. Hazato +9 more
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Prostaglandins, 1983
Abstract In the last three years a considerable amount of interest has been shown in the biosynthesis and pharmacological activity of a novel metabolite of prostacyclin (PGI2) called 6-keto-prostaglandin-E1 (6-keto-PGE1). The possibility that biosynthesis of 6-keto-PGE1 may contribute to some of the biological effects of either injected or endogenous
Philip K. Moore, Richard J. Griffiths
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Abstract In the last three years a considerable amount of interest has been shown in the biosynthesis and pharmacological activity of a novel metabolite of prostacyclin (PGI2) called 6-keto-prostaglandin-E1 (6-keto-PGE1). The possibility that biosynthesis of 6-keto-PGE1 may contribute to some of the biological effects of either injected or endogenous
Philip K. Moore, Richard J. Griffiths
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Prostaglandin E1: its effects on hepatic circulation in dogs.
Pharmacology, 1973The effects of intravenous, intra-arterial and intra-portal administration of prostaglandin E1 (PGE1) on hepatic artery (HA) and portal vein (PV) flows were studied in ...
A. Geumei +3 more
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