Results 111 to 120 of about 77,658 (288)

Micro‐ and nanomotors in biomedical applications

open access: yesResponsive Materials, EarlyView.
Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
wiley   +1 more source

Calcium transients trigger switch-like discharge of prostaglandin E2 in an extracellular signal-regulated kinase-dependent manner

open access: yeseLife
Prostaglandin E2 (PGE2) is a key player in a plethora of physiological and pathological events. Nevertheless, little is known about the dynamics of PGE2 secretion from a single cell and its effect on the neighboring cells.
Tetsuya Watabe   +6 more
doaj   +1 more source

Decreased multidrug resistance protein 1 and increased platelet activation in obstructive sleep apnea syndrome

open access: yesSleep Research, EarlyView.
There was a positive correlation between apnea/hypopnea index (AHI) index and platelet aggregation and a negative correlation between CD42b and multidrug resistance protein 1 (MRP1). Platelet activation was high while MRP1 expression was low in severe obstructive sleep apnea syndrome (OSAS) independent of smoking, age, and gender.
Cigdem Bayram Gurel   +8 more
wiley   +1 more source

The Biomaterial and Blood Clot Complex: A Crucial Early Environment for Osteo‐Coagulo‐Immunomodulation and the Advancement of Bone Biomaterials

open access: yesSmall Structures, EarlyView.
Various properties of bone biomaterials can modulate components of the blood clot (including the fibrin network, red blood cells, platelets, and the complement system) in vivo implantation, leading to the formation of a biomaterial–blood clot complex (BBCC) significantly impacting subsequent osteoimmunomodulation.
Zongpu Han   +11 more
wiley   +1 more source

Outpatient or Inpatient Setting for Cervical Ripening Before Induction of Labour: An Individual Participant Data Meta‐Analysis

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The optimal methods and settings for induction of labour (IOL) in terms of effectiveness, safety, and women's experience are still not elucidated. Objective To compare the effectiveness and safety of outpatient versus inpatient cervical ripening settings for IOL. Search Strategy MEDLINE, Embase, Emcare, CINAHL Plus, Scopus, Cochrane
Malitha Patabendige   +22 more
wiley   +1 more source

Induced Abortion After Previous Caesarean Section: A Scoping Review

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Previous caesarean section (CS) is increasingly common among women undergoing induced abortion. Aims To map and analyse existing literature on abortion safety, outcomes and management in those with previous CS. Materials and Methods Four databases were systematically searched from inception to July 2024.
Natalie Drever   +6 more
wiley   +1 more source

Endotypes in Immune Mediated Drug Reactions: Present and Future of Relevant Biomarkers. An EAACI Task Force Report

open access: yesAllergy, EarlyView.
ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga   +7 more
wiley   +1 more source

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